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>Help, advice, guidance on medications and dosages
>HRT related medical experiences and research
>Availability and pricing of medications
>Rational and scientific discussion

Please take the survey and help us determine the best medications, dosages, and treatment regime to get the results we want.
See the first post for a pharmacy list.

▶ Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Raw survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Anime Girl Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill Identification: https://www.drugs.com/imprints.php
▶ DrugBank Database: https://www.drugbank.ca/
▶ Basic HRT info: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ HRT target ranges: http://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Endocrine Society guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Callen-Lorde Guidelines (with flutamide): http://callen-lorde.org/graphics/2018/05/Callen-Lorde-TGNC-Hormone-Therapy-Protocols-2018.pdf
▶ WPATH SOC: https://www.wpath.org/publications/soc
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Breast development info: https://genderanalysis.net/resources/studies-on-trans-womens-breast-development/
▶ Blood testing (US Only): https://www.privatemdlabs.com/
▶ Blood testing (UK, Ireland): https://www.medichecks.com/
▶ Blood testing (Canada Only): https://bloodtestscanada.com/
▶ Blood testing By Mail: https://www.letsgetchecked.com/ - DIY capillary blood samples. Expensive.
▶ Lab test guide (reference ranges): https://www.healthcare.uiowa.edu/path_handbook/index.html
▶ FtM HRT guide: http://www.ftmguide.org/ttypes.html
▶ /HRTGen/ Archives: https://1drv.ms/w/s!AudRJceTA5C9fiPMDzSLX7xF9MI
▶ More Archives: List at 8ch /tttt/ HRT Info Dump sticky
Previous thread: >>12803591
>>
Medgirl131, whoever she is, has made a huge amount of high quality contributions to HRT-related pages on Wikipedia. We owe her a debt of gratitude.
Online pharmacy list:
inhousepharmacy.vu has been popular in the US.
eu-aibolit.com is a reliable site that ships to a lot of places. Good for EU anons. They list shipping rates for the UK, Canada, and US among others so I guess they ship there. http://eu-aibolit.com/content/15-usloviya-dostavki
shesalady.co.uk reportedly ships to Canada. You need to email the site operator to order. In the EU shipping times of two weeks have been reported. Email contact@shesalady.co.uk to order.
unitedpharmacies-uk.md seems to work for the UK.
There's also unitedpharmacies.md (US-centric) and unitedpharmacies.nl (Netherlands-centric)
alldaychemist.com is another.
http://lena.kiev.ua/ev/ has become popular for injections.
Less reliable/untested/poorly tested sites:
https://inhome-health.com/ seems iffy so consider them a last resort. Messed up orders have been reported. They are said to ship to Canada.
http://fast-pharmacy.com/product/Evista.html has raloxifene and some other meds but is expensive.
Possible source of a reasonably priced GnRH agonist: http://cherrypharmacy.com/product/buserelin-nasal-spray-analog-suprecur-suprefact-nasal-buserelin-acetate-150-mcgdose-180-doses/
https://amazon4health.com/ - expensive, no bica.
https://shape-shifters-eu.netlify.com has some satisfied customers.
I saw www.buyonlineventolin.com mentioned in a thread but I have know idea if they're reliable or not.
>>
>>12847312
link to the contributions on Wikipedia?
>>
>>12847519
https://en.wikipedia.org/wiki/Special:Contributions/Medgirl131
There are a *lot*.
>>
>>12847551
wow
>>
>>12847626
I know. It's really impressive. I wonder if she comes here at all.
>>
anyone found a good source of cypro which ships to the uk? unitedpharmacies only has hon doses.
>>
has anyone here used the "london transgender clinic" to get hrt?
>>
>>12847726
gendercare?
>>
>>12847652
https://www.unitedpharmacies-uk.md/Siterone-Cyproterone-Acetate-50mg-50-Tablets-p-789.html

it's not even remotely a hon dose? 50mg is plenty and more than enough to nuke your T. I ordered the other day and it arrived in like 4 days from Hong Kong without any customs charges, would recommend
>>
>>12847770
nah, it's a different place that seems to do hrt and other cosmetic surgery as well, they say they usually write a prescription after the first consultation
i'm just wondering if it's easier to get hrt there than go with gendercare since i'd like to be able to have a prescription in 3-4 months and I don't really want to have to go for a second appointment before i'm actually on anything
>>
>>12847882
oh cool it's come back into stock!
when i last checked they'd only got 2mg
>>
>>12847954
That sounds like the dose in the Diane 35 and similar pills with ethinyl estradiol in them. You wouldn't want them because of the EE anyway.
>>
>>12848289
yup, I only know one person here who takes EE. autistic, retarded, and trender. go figure.
>>
So as a non binary that’s trying to look more feminine but mostly just want to be androgynous, I’ve been looking at spiro for t blocking. Sadly have to self medicate since I live in the Deep South. Should I start at like 25mg doses a day and work my way up every few months? Or is that enough of a dose by itself?
>>
>>12848683
You have no idea what you're doing in any way, do you?
>>
>>12848683
If a mtf ends up androgynous after HRT they're one of the few lucky ones, stop memeing yourself and use what everyone else is
>>
>>12848683
Just use normal hrt. It's really not as powerful as people make it out to be and doctors mostly play up the effects because it ties into gatekeeping practices. HRTs effects are very slow and it's not that drastic. It takes many years before you can look back at yourself and see large changes.
>>
>>12848690
Not a fuckin clue. :|
>>
>>12848683
Just go full normal HRT, spiro is shit, cypro is much cheaper, but after 2 years, you should be looking at having an orchi tb
>>
is 25mg cypro and 2x2mg estradiol a good starting dose? im diying
>>
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Is this a good dose for starting? It is supposed to deliver 50 mcg a day.
>>
>>12853609
hondose
>>
I just started week 4 and my hips hurt, did i win the genetic lottery?
>>
Kinda dumb question but when getting a blood test, should I ask for Total testosterone or Free testosterone ? Estradiol is straight to the point I guess
>>
>>12853954
Total
If you want free T calculate it from SHBG+albumin+total T (it's just as accurate as a direct test, if not better)
>>
>did several dozen injections fine
>do one just now
>no matter how much pressure I apply it just keeps leaking out for minutes
this has never happened before what is going on
>>
>>12856069
yeah pretty sure MOST of it came back out, this is nuts
is this a resistance building thing I've heard about?
>>
>>12856112
Did you change up your injection site?
>>
>>12856133
I've been moving around my deltoid a little and switching up left/right
is that what this is?
>>
>>12856147
I only have experience with injecting in glutes but yeah i remember you have to change it a bit since putting a needle in there will create scar tissue or something. Although im not sure since you say you are changing injections spots. Hmm, are you doing one of the techniques too? I mean sometimes you do fuck up injecting, could be it was too shallow but if you use a technique idk which one works on delts but z-injections usually worked fine for me to keep it in there. Look into that if you wanna, would suggest going on steroid sites to see how they do it, since they are also injecting and do it themselves.
>>
So if I'm reading the sheets properly, would 50mg Cypro and 2mg Progynova be a dosage that's proper?
>>
>>12856216
that's a hondose, increase E
>>
>>12856332
4?
>>
Is Lena's Een fine to inject subcutaneously?
>>
>>12856340
>>12856332
Anyone? I can't afford to be doomed
>>
>>12856340
For oral E you can start at 2mg but slowly increase to 6-10mg over the course of your first 6mos.
>>
>>12856751
10 sounds like a lot, doesn't it? That'd be 5 pills.

Going up by 2mg a month sounds about right? Should I just go to 6 now? I've been on for a month.
>>
>>12856767
Oral E has very poor absorption and most gets converted to estrone. Only around 5% actually gets absorbed as estradiol so 10mg actually isn't very much
Ideally you should not use oral E since it's not very good for mtf purposes.

Just go up to 4mg for now and increase to 6mg after 3mo
>>
>>12856787
What would you suggest that isn't a needle? Severe Phobia. I wouldn't be able to do it.
>>
so, anon who had their injection leak out a bunch.... should I just inject again somewhere else? full or half? inject a few days early next time, instead?
>>
>>12856849
Patches are good and pretty cheap usually.
Gels are good if you can afford it. They tend to be pricey and the gel doesn't have a lot of estradiol in it so you need a ton.

I would say you could try sublingual but so many people have trouble with it that I think other forms would be better.
>>
>>12856907
So basically Patches>Gel?

I'm very ignorant to patches. I haven't done almost any research into it. Are there any by name that you would suggest? I'll pick some up right away.

Also, thank you so much. There aren't many nice anons that take the time to help like you. I really appreciate it.
>>
>>12856944
Patches are identical to gel in terms of efficacy assuming you can check your levels and adjust dosages.
With a prescription a lot of people go with gels just because they don't leave little glue blobs on your skin and if you're not paying then who cares if you're blowing through tubes of the stuff every day lol

Where are you buying your hrt from? There's a lot of different brands out there.
Generally for trans stuff get no less than the 100ug patches though. The 50ug patches are more for post-menopausal women. Often once you're 3+mo in you may need 2 or 3 patches, maybe even 4 if you're really unlucky.
>>
>>12856999
Unitedpharmacies and self med. I know it's not ideal but it's pretty difficult to get any sort of care down here. I've tried. Unless I move it's not happening and work makes that unlikely.

As far as stuff on the skin, that's whatever. I couldn't care less about that kind of thing. I'm open to practically anything as long as it's not sticking something inside me (needle.)
>>
I just started hrt and im currently on 50mg of cypro and 2mg of estrofem, should i increase my dose of E to 4mg or 6mg a day in a month or two in?
>>
how long should i wait to start on hormones after my last cigarette?
>>
>>12848406
yea only autistic retard trenders take the best HRT available to them
>>
>>12856944
Don't know if you're still here but I just got back from an outing.

I'm looking at 100mcg Estradot. That's what I should be aiming for, right?
>>
>>12859037
Meant to quote>>12856999
>>
My nipples and chest are getting really sensitive and hurt a little, is this normal for two weeks?
>>
>>12859665
you're growing boobs dummy what do you think
>>
>>12859675
I know but it feels sudden
>>
>>12859742
I got my buds in less than a month. the 2-3 months thing is more of a conservative estimate
>>
>>12859753
Ah that's reassuring
>>
>>12859037
Yes that should be fine.

Some people also buy medical tape to paste over top if you find they peel off. But normally it's not a big deal. I think tegaderm is what I've heard people buy.
>>
>>12859742
mine started same time as you and then week 3 i got saw hips, i'm only 1 week ahead of you, we be transition sisters :D
>>
>>12853537
Yeah, you can start with that. Though it's common to go with 1x2mg for a few weeks to give your body a bit of time to adjust. I haven't seen any hard science to back that up though.
>>12853609
You could start with twice that. If you did go with 50 you wouldn't want to stay there for very long since it won't do much for you.
>>12853833
Not necessarily. Time will tell.
>>12856216
You should be able to go with 25 mg cypro. You could start with 2 mg progynova - though I'd use it sublingually - cut/crush the pills as necessary to make that work. You'd want to go up pretty soon though. Long-term you'd be looking at 4 mg and up, with at least 6 mg being what you'd likely end up with.
>>12856711
It should work subq
>>12856849
Transdermal. Patches or gels. Some people get better results with scrotal application.
>>12856907
Sublingual gets easier after you've done it several times and you learn what works best for you. Keeping it under your tongue can be hard at first, but it gets easier. Splitting pills helps them dissolve more easily.
>>12856944
The main advantage of patches is that it's easier to get consistent dosing and steadier levels. But they can be annoying, and cause skin irritation, and can fall off.
>>12857206
Go to 4 mg first. If you can get blood tests do so before going higher, though there's a very good chance you'd need 6. You could also go down to 25 mg cypro.
>>12857501
You don't really have to wait. Smoking is mostly a problem with oral pills. It has little effect on transdermal and injections.
>>12859037
That's the largest dose available with patches. You can start with that but you'll probably need to go with two at a time. If you can blood test that will help you know what you need.
>>
>start hrt at 18
>0 hip growth
JJJJJJUST
>>
Is androgen receptor upregulation a risk with bica because of the plasma test levels?
>>
>>12860740
I doubt it has ever been researched and it would be difficult to determine given that bica itself binds to androgen receptors.
But receptors are not permanent structures in the body. The turnover rate for E/T receptors is less than 12 hours.

Bica could theoretically lead to some upregulation given that receptor concentration changes in response to transcriptase activity. Since bica prevents transcriptase activity it's likely that receptor concentration increases.
Though your body doesn't have an infinite supply of receptors. I doubt you would get much more than a 5% increase at best unless you have weird genetic diseases. Your body utilizes protein to make receptors and it's a pretty minor process in the human body. Upregulation/downregulation is unlikely to proceed past a few percentile changes as it is a waste of energy.
>>
>>12860590
How long have you been on HRT
>>
>>12860814
since Christmas
>>
>>12860818
what were your test levels when starting?
>>
>>12860829
didn't measure, I'm on 1*100mcg patch now tho and t is 1.98nmol/L so I think it was maybe low before (?)
>>
>>12860755
This is a huge relief. I was worried I gave myself AR upregulation due to discontinuing dutasteride. Ever since then I've been super horny and dicc is working again.

Thank you.
>>
>>12860884
Wait dicc isn't supposed to work? I don't get erections super easily any more but it works.
>>
>>12860892
It worked fine with very high estradiol levels and almost no T, but when I took duta it killed it.
>>
>>12860884
There is no established mechanism for upregulation/downregulation of receptors so I doubt it is a big deal.

As far as the extent of the effects the change in receptor concentration it is technically statistically significant, but not enough to have been discovered any time sooner than the past decade. There's no distinct mechanism for it and any mechanism we have discovered so far seems to be more coincidental rather than evolved. Your body wouldn't expend energy on such a useless process so there's no genetic advantage to it existing in the first place.
>>
Is a few years really that important in your 20s, when starting? Like, is 22 vs 24 that big of a difference?
>>
>>12861051
Yes. Hair loss and hip bone fusion. Brow ridge can also become more prominent during that period. 22~25 is actually fairly critical for mitigating androgenic damage.
>>
>>12859821
Alrighty, I think I've got a fair grasp on it. Thank you!
What's the lifespan of a patch? I've seen different times online. Nothing really consistent.
>>
Okayyy bloodtest is done, 2h before my next injection:
E2 : 682 pg/ml
T : <0.03 ng/ml
It's kinda high right ? Should I lower my dosage ? I'm on 8mg/5days EV injections
>>
>>12862546
yeah that's high, you could probably try spacing it out to every 7 days or do 5mg/5 days
>>
Do I need to shake my enanthate vial or something? Im getting subpar results on it compared to when I first started, next injection will be later today
>>
I'm at 180pg/ml, is that good or bad?
The hrt range link only gives a bunch of numbers with no clue whats ideal for MTF transitioning.
>>
Progy vs Estrace??
I used to be on Prog now im on Estrace. Will i notice a difference??
>>
>5 months on HRT
>Right boob is starting to look like a boob
>Left boob is nonexistent

I'm starting to worry.
>>
So when they say replace patches twice a week, does that mean wearing them for 3 1/2 days each? Stupid question I know but I'd like to know.
>>
>>12863327
fine level
>>
should've answered all in one post duh
>>12863805
irregular growth is normal, even for cis. one side will most of the time always be bigger. dw
>>12863999
correct
>>
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would 50mg cyproterone every other day and 25mg spiro every day work for suppressing T? I accidentally fucked myself into buying 100mg pills and I can't split them into 25mg every day.
>>
>>12863792
ev in prog is a bit less effective (around 30% but don't quote me) than eh in estrace so yeah you'll get better result
>>
>>12864141
50mg cypro should be enough, it has a long half life of at least 36 hours.
>>
Visit :https://17beta.top/en
It contains Info about hrt,transition and much more info about that topic
Give it a read it may interest you.
>>
>>12864343
>Ksenia
>>
>>12864452
No Karen
but i know her
>>
Alright everyone this is going to be a bit of a controversial post I know but I have absolutely no way of getting HRT at the point of life and place where I am at. However I know some people into a more alternative / vegan lifestyle, and have slowly introduced the topic to one of those, and have heard this regarding natural supplements:

> Saw Palmetto
Should decrease the dreaded DHT and body hair - I've had it for a week and see no difference if anything seems to have increased, but I know a month is the least to see effects, should I keep on it?

> Reiki
Decreases DHT and T, supposedly. If so its a god blessing.

>Pumpkin Seeds
Should reduce DHT

> Licorice, green tea and spearmint
Should reduce DHT and T.

Are any of those true or am I being played for a sucker? Even if not extremely effective Ill take all I can, I hate hate the effects of T on me. I dont have any choice for a proper HRT, live in a small town and dont have a mailbox just for myself.
>>
>>12864478
>her
>>
>>12864515
If your in the US just pay for a p.o. box
>>
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detransitioner here. if i were to completely stop AAs and E yet continue to take dutasteride, could i keep my hair gainz?
>>
>>12864515
Licorice is toxic in the amounts you need to suppress T.
The rest of that stuff might suppress dht a bit but nothing compared to fina/duta.
>>
>>12864515
all of these are just more expensive and less effective than normal HRT and there's no reason to get any of these
>>
>>12864478
Ksenia is a nutcase.
>>
For some reason after switching to doing my injections subcutaneously my results have improved from the last few times i was doing it in the deltoid. Could there be a reason for this besides me just messing up the deltoid injections?
>>
>>12864784
As far as what I have heard fina/duta doesn't actually stop mpb it just slows it. In some people it slows it enough that the changes are unnoticeable. But I've heard cis guys say they still have a tough time preventing the "mature hairline" (temple recession) even on fina/duta.
>>
>>12864998
i've restored pretty much to a NW1 and while the hair is dense, it's still translucent/thin so it still looks like a NW2. should i continue on HRT until the hairs darken and become terminal?
>>
>>12864907
>>12864770
>>12864843

I dont live in a place I can get real hrt and cant get a po box its a po-dunk and not in the us. What about female birth control, I know its very strong on its own but if I cut in half or quarters?
>>
>>12865019
How long have you been on hrt? Are you sure you're not actually trans? I don't think there are many cis guys that would use hrt willingly.
>>
>>12865049
14 months. i don't want the breasts i grew and i don't like having reduced sexual function. everything else about hrt i've enjoyed though, especially preventing and reversing hairloss.
>>
>>12865069
You should probably consider talking to a therapist. That's a very long time to be on hrt for a "cis" person.
Not saying it's not possible but if you are actually trans you shouldn't stop hrt.
>>
>>12864965
subcountaneous absorbs more slowly. that's why it's the better choice for EV atleast. 5mg/7days is enough for me.
honestly I don't know why anyone would prefer im over sc for many many reasons.
>>
>>12865155
Explain. I know nothing about that.
>>
My parents are getting pretty suspicious so im going to take a blood test to prove that theres nothing wrong, will 2 weeks be enough for getting testosterone to a normal range?
>>
>>12865838
Where do you live that doctors are willing to give blood tests just because you requested it? Especially hormone tests. That seems odd. Normally doctors get very suspicious if you request hormone tests
>>
Guys I have to keep increasing my cypro dose my body keeps adapting??? I just went up to 100.
>>
>>12865029
order it poste restante (means you're getting it from the post office) then if there is a post office within your reach. That's what I did.

>>12865838
same question, what time is required to get T back into normal range if you go off hrt for a moment
>>
>>12866870
You can buy one from privatemedlabs or just tell your doctor youve been feeling symptoms of low t like lower libido and depression and ask to get it tested
>>
got off hrt because i decided i value my social life more than a mental illness.
now the issue is, i am not feeling too well. i get nosebleeds every 2-4 hours, i can hardly walk for longer than 15 minutes, my bones hurt like hell and i can't sleep more than maybe 2 hours a day.
is there any way to go back to normal?
>>
Does cypro 25 mg lower better than 12.5 mg.
>>
>>12863327
>>12864081
>fine level
Don't lie to her. Below 200 pg/ml is on the low end, and above 350 is high.

180 pg/ml would only be remotely acceptable as a transition dose if she's taking cypro or a GnRH analog. As monotherapy, with spiro, or even with bica (assuming safe ish dose), it's too low.
>>
>>12848683
Where in the Deep South? I thought I'd have to self-med, too, but I found an informed consent place near me that specifically states they support enbies. I walked away with a script after my first appointment.
>>
>>12868422
Yeah that isn't supposed to happen
Ask your doctor
>>
>>12868779
I take cypro and my T is nuked.
>>
>>12869170
That's good as far as preventing masculinization. But I believe it's an insufficient sex hormone level. It might work somewhat for transition with a decent anti-gonadotrophin like cypro, but it'll probably lead to earlier signs of aging than targeting, for example, 250 pg/ml.
>>
>>12864920
Nah she is fine
>>
>>12869269
I'll see if I can get my levels up a little bit, thank you.
>>
so i got bloodwork done when should i get my results back??
>>
Just got my bloodtest results after a bit over 1 month on 25mg cypro and 2mg estrofem (bucally, split throughout the day).
E2: 284 pmol/L
T: 1.14 nmol/L

Should I up my estro dose to 4mg now? Also, can I reduce my cypro dose to 12.5mg?
>>
>>12870012
yes and yes
>>
>>12869978
What made you think this is a good place to ask a question like that
>>
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What hormones do I take if I want to:

1. not sterilize myself
2. negate the effects of ageing
3. feminize my appearance
4. not grow breasts
5. not end up with osteoporosis

Also I have fibromyalgia so would hormones be save?

Thank you in advance if you provide me with any assistance in wrapping my head around the confusing morass that is HRT.
>>
>>12870820
Doesn't work like that, sorry.
>>
>>12870820
Shotgun to the face. If you still recognize masculine features after one dose, take more
>>
>>12870820
The hormone receptors are all over your body so why do you expect to choose which body parts should be affected?
Best solution would be freezing sperm and getting a mastectomy if your boobs grow to large.
>>
>>12870820
You recognize that we're not living in some ulta technological utopia where medicine will give you any results you want and that you need to use the same shit as everyone else, then you bank your sperm and get a mastectomy
>>
>>12870888
>>12870893
Does raloxifene not suppress breast growth?
>>
>>12870966
Not fully, it gives you cone tits
>>
I injected 0.44ml of Lena's estradiol enanthate in my belly (subcutaneously). It's been 3 hours and sometimes it randomly feels sore or stings. Should I be worried?
>>
>3mo ago estrogen was 242.3 pg/mL
>1wk ago estrogen was 516.0 pg/mL
>each time blood drawn 1 week after previous injection
>feel like body hair is suddenly growing much faster than it was despite doubling my estrogen
What gives? It slowed down massively for months and now it suddenly seems like it grows 2-3x faster
>>
>>12871125
Not really
>>
>>12871125
No im doing the exact same as you and it usually feels sore on the first and second day then it leaves a lump under the skin if you feel the injection site but isnt visible otherwise.
>>
>>12871252
>>12871287
Is it also normal that a little came out? (I pulled the needle out directly after injecting)
>>
>>12871330
Yes, leakage is completely normal. You can take steps to reduce it
>Leakage will be minimized using a thin needle, using 90° needle insertion in the abdomen, injecting maximum 800 µL at a time, and waiting at least 3 seconds after the injection until the needle is withdrawn from the skin.
>>
>>12871356
I use 29G needles, and 45 degree, I don't think I have enough belly fat for 90 degree...
>>
Bica mono yes/no
>>
>>12871385
No, don't you want estrogen?
>>
>>12871362
>I don't think I have enough belly fat for 90 degree...
You can just buy a shorter needle
>>
>>12871422
Mine are 12.7mm fixed needle insulin syringes. Bought a bunch of them >.>
>>
>>12871434
Then I guess you can't do a 90 degree injection
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>>12871233
those levels are WAY higher then recommended. I wouldn't be surprised if for some-reason it's growing faster because of your elevated estrogen levels
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best syringes
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Do I need to shake my enanthate vial every so often? Just wondering whether it needs that kinda maintenance after two weeks just staying still
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>>12871400
Feels uncomfortable asking for estrogen in the pharmacy, what would the effect of mono bica be?
>>
>>12871470
Source? I don't see that as a symptom anywhere
https://www.healthline.com/health/high-estrogen
>>
>>12871663
You'll look the exact same, but with osteoporosis and chronic fatigue
>>
>>12871910
But I won't develop further will I.
>>
>>12871582
Can it really hurt to just shake it some before use? As long as you don't dissolve any air into the solution, I can't possibly imagine any reason not to do it.
>>
>>12871913
You will to a certain extent.
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>>12872427
How so
>>
Does taking cypro lead to overproduction of adrenal testosterone? Or something?
>>
>>12872476
T blockers doesn't stop puberty and development. If you're in your twenties the bones in your face will keep growing larger in certain areas, and if your growth plates haven't fused yet you're going to become taller than normal. The development is going to happen, T and E just steers it in certain directions.
>>
>>12847312
>Medgirl131, whoever she is, has made a huge amount of high quality contributions to HRT-related pages on Wikipedia. We owe her a debt of gratitude.
I know "her". She's a tranny from #velvetandlace channel on freenode IRC, much of a reddit fag too.

She can't even draw SVGs.
>>
>>12872897
What if I'm 18? will it stop more face changes?
>>
>>12847312
>>12872920
She's also a person behind the MadGenderScience wiki: https://madgenderscience.wiki/
>>
>>12872927
Yes , your bones complete fusing around 22 so if you start hrt before then it will change your bone structure still, as long as your taking an estrogen with an AA
>>
>>12865341
there was some study someone posted a while back showing slower uptake for hormones (i think it was growth hormone or some shit) injected with sc compared to im
idk why but i guess because muscle is more vascular and moves around more so the depot gets released into the bloodstream a bit faster or something
>>
>>12868422
kek you deserve it
>>
>>12871906
>source
his ass
>>
>>12872920
she sounds based and you sound like a jealous bitter hon
>>
Hello you lovely anon's, basically i will not be able to start hormones with medical guidance for another year so here i am. I'm mtf and I've been reading up on hormones as you do, and i have stumbled upon the idea of a sorta hormonal cocktail that in theory should get good results. Progesterone, human placental lactogen (hpl), and prolactin all play a role in pregnancy, they all play a role in lactogenesis or milk production which is intimately tied with mammogenesis or breast growth. so my theory is that if you where to after some time on the normal estrogen routine then change it to heightened levels of progesterone and estrogen, as well as hpc, and then after a while prolactin, you would be able to mimic pregnancy effects on the breasts and achieve further mammogenesis and maybe even lactogenesis after you then drop your progesterone and estrogen levels back to more normal levels and completely drop hpl and only stay on moderate levels of prolactin for the milk and perhaps the smallest bit of oxytocin for the milk ejaculation. anyways i just wanted to put that out their and see if anyone has had this idea in the past and maybe looked into it, besides that i was wondering about what would be a good tblocker and estrogen pills and dosage and stuff and for a store for the us. sorry this is a lot. i believe i've read that patches for estrogen is the safest one and allows you to go on higher doses without fear of blood clots but i'm not sure about its effectiveness or even what strting dosage to get or where to work up to, any and all help would be appreciated, frankly just being acknowledged is great, not sure why i'm saying that though, anyways cheers my lovelies.
>>
>>12870820
>1. not sterilize myself
>2. negate the effects of ageing
>3. feminize my appearance
>4. not grow breasts
>5. not end up with osteoporosis
Pick 235 or 145
>>
>>12873582
>patches
Start with 100 mcg for the first 2-4 weeks, then raise to 200 mcg and get blood tested.

After you get your results back, if E2 level is below 250 pg/ml, raise to 300 mcg, test blood, repeat until E2 is 250-350 pg/ml. It will likely take 3-6 patches.
>>
>>12871470
I'm only on 10mg IM/wk

I've never heard of estrogen causing excess hair growth when there's too much
>>
>6 months HRT
>testicle a feel kinda big
>fap
>testicle go back to being tiny again

What's the exact scientific reason for this?
>>
is it possible to overdose on cypro if you immedietly start with a high dose or am I being paranoid?
>>
>>12875313
As I understand its normal to start high with cypro(50mg) and then reduce the dose to 25 or even 12.5 depending on your T level. as it is a very potent AA but is also rather heavy your body.
>>
>>12874828
your gender was in the balls all along
>>
I badly want to transition. But I'm 30. Will there be significant changes?
>>
>>12876040
>>12793177
>>
Is there any proof that this increases your interest in men sexually? I'm gay but won't go out of my way to get laid type of gay.
>>
>>12876113
every transgirl I know has had some discernible level of sexuality change anywhere from simply occasionally thinking about being w/ men when they never did prior, all the way to full on sexuality flips over to liking men.

it's not a hard and fast rule, but it happens pretty often.
>>
>>12876040
You'll get breast growth and fat distribution changes. If you have a skinny frame you have a much better shot at passing than someone who's 18 with a big frame. Pretty much everyone requires ffs to have a passable face, however. Faces become sexually dimorphic at very young ages.
>>
>>12876378
Thank you. I hope I don't grow limb when I transition I'd still like to experience a wild sexual future
>>
>>12876420
Okay this sort of makes me feel better. Although I do not have the skinniest of frames but it'll be a work in progress. But the legs and ass I do have, guess that and the face is all that matters to me most right now.
>>
>>12876498
>Although I do not have the skinniest of frames but it'll be a work in progress
That's not how it works, you can't change your frame after puberty.
>>
>>12876598
I meant I can make myself look thinner in other ways. Posture, dressing etc etc.
>>
>>12876113
>>12876378
Hon science, don't fetishize this.
>>
>10mg EV/IM Estradiol /week
>25mg Cyproterone /night
>100mg Progesterone /night
>10 months on hrt
>530pg/ml Estrogen trough level
Since my estrogen is over 500 do you think I'd be fine to drop my cyproterone? They didn't test for testosterone levels, but 6mo ago it was only 47 ng/dL so in female range, but that was the week before I was put on injections and estro was mid-200s.
>>
>>12876696
It's only fine to drop your cypro if you've confirmed it's fine with blood tests. It really isn't a decision you should make based on intuition. If your question was meant as whether it's okay to drop cypro for a while so you can test your blood about whether it's fine to stop using it, then yeah, go ahead.
>>
Can I cut off my weewee and reattach it later on?
>>
So what's the consensus on injecting calcium chloride into your testicles? Good or bad idea? Health risks?
>>
>>12877043
Generally a bad idea, if you succeed, don't tell others to do it and if you fail you are jeopardizing tranny rights even further.
>>
>>12877050
What would failing and succeeding mean in this context?
>>
>>12876781
LOL no
>>
>>12876781
Worked for John Bobbitt
>>
>>12877065
Not dying and castrating yourself, adrenal test exist so youiu might need AAs after a while.
>>
>>12877245
Now I'm confused, not dying equals failing? Or castrating yourself equals failing? Isn't castration the entire point
Is it possible to die doing this?
>>
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everyone I'm so confused...

Basically I did another injection today and I wanted to draw 0.32ml, so I took the syringe out of its packet, pulled it back 0.32ml, stuck it in the estradiol vial, compressed it back to 0ml, turned the vial and the needle upside down, and slowly drew the vial. The problem is that a gigantic air bubble formed and I couldn't get rid of it, the air bubble was so big that I actually drew more estradiol to compensate for it. Pic related is the needle before I injected myself. I don't know why this gigantic air bubble keeps forming

secondly, I'm convinced that I actually injected more than 0.32ml. Above the air bubble there seems to be a sizable amount of estradiol.

Once I drew a needle and tried pressing it down until all of the bubble came out, and instead estradiol just kept coming out long before the bubble went.

I'm beginning to wonder if the gigantic bubble is caused by an air space in the upper part of the syringe, so when I draw the needle back the bubble in the air space moves back and filles with estradiol, but I don't know for sure if this is what's happening

so basically, what I want to know is, did I inject myself with ~0.32ml, or did I inject myself with more thanks to the space at the top of the syringe, and how big is that space?

I'm so sorry for the retarded question, please answer, if this doesn't make sense please tell me that it doesn't so I can rewrite it, I'm getting so confused
>>
My doctor scripted me 200mg spiro and 6mg e/day a while back
Recently I've been reading a lotta stuff here about how garbage spiro is, and I have to ask, is it just memes, or is it really that bad? Should I try to pester her into changing my script? She said she could do finasteride instead of spiro, but I didn't think it worked like that...
>>
>>12877338
spiro is terrible, but you're mostly out of luck in the US if you're not willing to shell out big bucks without a script.
>>
>>12876730
I only asked because I keep being old 10mg is more than enough for monotherapy but ya

Super worried about dropping off it and test going back up. LH/FSH have been nuked for probs 7mo and test has been in female range for as long. Guess I'll just stay on my cypro
>>
>>12877338
>finasteride instead of spiro
What?!
>>
>>12877411
The dosage needed for monotherapy varies from person to person
>>
None of you actually give advice when people ask this general is shit and pointless.
>>
>>12877338
https://moderntranshormones.com/2018/01/01/whats-wrong-with-spironolactone/
>>
>>12877344
I will have to see about convincing her otherwise, then
>>12877473
Yeah, that's why I was so confused...
>>12877587
I haven't had a chance to verify the sources yet, but if they're all good I'll show this to my doctor
>>
>>12877260
You could hit a vein, your body could react badly, etc, failing would be dying of course.
>>
>>12873582
A cheaper route is just prog, domperidone and something that boosts hgh like mk-677. Inducing lactation isn't exactly witchcraft.
Where would you even get hpl? Whats your reason for hpl specifically?
>>
Is it true nicotine inhibits the body's response to estrogen? If so, is there any difference between nicotine delivery methods?
>>
How effective is 12.5 mg cypro compared to 100-200mg of Spiro?
>>
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so what brand of spearmint tea are you buying, anon?
>>
>>12878722
I like to grow my own blend of spearmint, green tea and ginseng, how about you anon?
>>
>>12878163
Dunno about it inhibiting the response to estrogen but your best bet is to just quit all forms of nicotine

Nicotine itself in any method of administration is not great for your skin which is like basically the first thing people notice about you aside from maybe hair

Also if you are on oral pills nicotine increases the risk of DVT.

Anecdotally I used to vape about a 120mL bottle of e-liquid every 2-3 weeks and when I quit my tits started growing again after 2 years of being stagnant. Could have been any number of things that caused that but I know for certain my skin has improved after stopping vaping and it's basically an extra $100ish in my pocket every month or so
>>
>>12879136
not sure yet, haven't started. I'm growing some mint i found outside but there's not enough of it to use. is there a strain or subspecies of spearmint you're growing?
>>
>>12873709
>started HRT 2 weeks ago
>50mcg patches, next appointment in 2 months
I feel cheated, fuck my life. If I can't get cypro next appointment and they increase my dose to like 100mcg I'm gonna rage then DIY.
>>
Seriously how do I stop giving myself bumps/nodes under the skin when I inject subcutaneously?

>first 3-4 injections were fine
>every one since that have a bump/node under skin

what am I doing wrong, I follow guides and videos on how to do it but it keeps happening
>>
>>12879949
I grow both banana mint, and just plain old spearmint. Ive tried the mint in tea, its not too good vs spearmint, but its leaves smell just like banana.
>>
>>12880366
25mcg patches next appiontment in 3 months :////
>>
Hey guys...is there a link to a good guide for DIY HRT? I mean start to finish. Can not afford a doctor :|
>>
>>12879198
Fascinating. I quit smoking a year ago for my hair and skin but I switched to vape and I’m worried it’s messing with my ‘mones
>>
>>12880745
that's kinda cool, i like how mint strains are named after fruit like pineapple and banana and stuff. I like the square stems and symmetry of them too.. where did you get your plants?
>>
>>12881004
vaping is almost certainly better than smoking, but quitting nicotine entirely is going to be better for your skin/anti-aging/transition long term no matter how ya cut it imo
>>
>>12877570
where is your post
>>
>>12881090
I got a few of my plants off of this website. https://www.mountainvalleygrowers.com/
They are pretty reliable, and it ships pretty quickly
>>
>>12880408
inject deeper

>>12880972
look at the resources in the OP, read the OP pic, and read the first reply
>>
>>12881277
I looked but couldn’t figure out what I was looking for -_- I’ll check again. Sorry, I’m a little dumb
>>
Hey guys. Will it be possible to still act 'manly' while transitioning?

Asking for a friend
>>
>>12882071
yes ofcourse
>>
>>12882071
>>12882478
okay to add to this, you'll probably feel less aggressive and more calm instead, on top of this you'll probably find it easier to cry. This doesn't mean you're going to turn into a sub bitch unless that's what you want to be.
>>
>>12882482
Reason why I am asking because I don't want to get fired the first year while transition at my job.
>>
>>12882505
what job are you working?
>>
If I'm in Canada, is it worth it bothering with professionals in order to get cheap meds or do I just go DIY? I'm prepared to pay a decent amount, as long as I don't have to sell an arm and a leg, but not wasting cash is always great. I'm also living in Alberta, which is not exactly positioned well politically for this sort of thing.
>>
>>12882578
A junior accountant for retail company.
>>
>>12882627
How do you people even trans in that cold weather?

I love Canada though wish I could go live their and spike off their free health care etc etc.
>>
>>12882637
lmao you're not going to turn in a parody turbo fem gayboymoder from HRT alone, especially if you're actively trying to behave normal.
>>
>>12882627
Forgot to mention, I also have a mild heart condition which is, for some reason, taken incredibly seriously despite it not even being confirmed I have it, and I take meds for it, AND a list I just checked doesn't list any HRT meds as known dangers.
However, my parents have always been overly concerned and same with doctors, so they might just refuse a prescription anyways.
>>
>>12882674
Okay, good to know thanks. I'm sure they all know I'm a faggot anyways.
>>
>>12882679
Get checked before you begin with any hormonal medication. I'm no expert but it can't be good.
>>
>>12882698
I have been getting checked, since I was born, and recently they've been saying the initial tests were wrong. Unfortunately, to get tested again I'd have to get DNA tests done through the US, and catch me dead if Steve Jobs gets to clone my ass.
>>
Asking for a friend, she's still in the middle of puberty, but doesn't want me to get her hormones because she's in a bad situation where if she got outed, it would be pretty much over. Would 1mg estradiol and cypro make her grow boobs?
>>
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>>12882819
>asking for a friend
>>
>>12882819
also yeah I think it would
just wear stuff over it
like loose clothes or a binder
they won't be very big at all
>>
>>12882819
Yes it would, especially if you're young enough to still be in puberty.
>>
>>12882862
>tfw you don't know the rules
>>
>>12879198
Smokers will have at least 30% less e in median. It also affects concentration in tissues.
>>
>>12882873
>>12882892
Wouldn't the development be slower with 1mg something like 9 months or so, or would you need 0.5 mg
Basically a trap, wat do?
>>
If I work towards getting a feminine body, would I need to get rid of all my current body muscle? I'm not big but kinda muscular. Or can I leave it and watch it disappear with time?
>>
>>12882482
Why do I have random fits of aggression then? granted I've been angsty before but now I'm throwing stuff.
>>
>>12883192
if you're taking E you're gonna get tits, that's just life
cover it up or take AAs only until you get older and move out
if you're still in puberty, that will actually be quite effective, though your bones may suffer
>>12883316
muscle just goes away over time, hrt will speed that up
if you don't exercise no new muscle will build, just wait it out

now here's my question: is bica a good idea? i've had it recommended to me but if it only blocks T is that enough?
i know spiro sucks but what would a better alternative be?
>>
>>12883479
I think it also feminizes slightly if you are young.
>>
>>12883479
Literally anything is better than spiro.
>>
>>12883454
I... don't know

I still get angsty, but pre HRT is when I was punching walls and thinking about how I want to kill people

>>12883316
>>12883479
>muscle just goes away over time, hrt will speed that up
>if you don't exercise no new muscle will build, just wait it out

I should say, estrogen isn't very good for building muscle mass, but it's perfectly servicable for maintaining it. Expect some immediate strength loss, but don't expect significant muscle bulk loss until a long time, like 2+ years

also eat at a calorie deficit and don't eat more protein that necessary (but don't undereat protein that shit is important for more than just muscle)

Bica is a fantastic AA
Effectiveness: Cypro > Bica >>> Spiro
Side Effects: Bica >>> Cypro >>> Spiro

only downsides to bica is that you can't bloodtest to see if it works, and it won't permenantly/long term impair testosterone production and pickle function, impairing testosterone production means you can lower your dose after several months and save money/avoid side effects, impairing pickle function is important if you have bottom dysphoria

Bica also leads to the aromatisation of testosterone which means slightly higher estrogen levels, a nice bonus.

Bica is also the only AA that can be taken by itself with incurring horrible health risks, however this will not achieve much feminisation.
>>
>>12883509
is there any better info on the "GnRH Agonists" in the OP image?
they might be cheaper, right?
>>
Could coffee be affecting my hip grow? I've had some pain so far.
>>
>>12882482
>This doesn't mean you're going to turn into a sub bitch unless that's what you want to be

So you’re saying that if I *do* want to be a sub bitch, this’ll definitely do the trick
>>
>>12883454
>Why do I have random fits of aggression then?
Being less apathetic most likely.
Try meditation, mindfulness exercises.
>>
>>12876684
anecdotally, it does seem to happen tho
>>
I was prescribed 20mg estradiol valerate every 14 days from planned parenthood, but I was thinking it would be better to do 10mg/7days because of how short acting estradiol valerate is.
I'm also taking 100mg sprio every day as well.
For reference lena recommends 7mg/5days E valerate (note this is a very slightly less than what I'm taking) for monotherpy
>>
>>12883944
sorry I forgot the question
do you think this a good idea and also should I lower the amount of spiro I'm taking now?
>>
i'm starting to get 1 or 2 zits on my face after 6 months of being acne-free, and what little stubble i grow is turning black. what gives? are my AAs not working anymore? HRT for 14 months btw, 25mg cyproterone acetate, 0.5mg dutasteride, (2) 100mcg E patches.
>>
>>12881276
thanks anon
>>
I'm beginning my transitioning soon. But hear me out. I do not want to go full on. Just enough to have a nice feminine body and appearance. So I have a couple of questions.

Is there a possibility that I can use estrogen at a certain doses that won't give me breasts?
Are the patches the best way to go? I heard it slowly messes up your liver with oral intake. So i try avoid that. Does it really mess up your liver that bad or am I overreacting?
I won't be getting my estrogen very soon so I thought I should take some natural menopause substance made for well 'menopause' just to get the wheels turning. Is this okay? Will it have a bad effect kn me if I use it for two months?
I got myself Finasteride. Want to use it for hairloss purposes and T termination. Is estrogen and Finasteride safe being used together over a long period of time? Also Finasteride has a bad rep for libido impact. What are my chances of not going limb and useless? I would really like to keep my sex drive. How long does it take for it to have such an impact?

Sorry I know it is a lot of questions.

I'm on Epilim and olanzopine for my mental illnesses. Ritalin as well but I'm going to stop using Ritalin. Will my current medication and my hrt meds mess me up together or shouldn't I be worried? Like have some bad emotional effect or something?

I have lots more question but I'll take on them later.

Last one for keks
Will I become clumsy like a woman?

I mentioned that I don't want breasts. But it is not the end of the world if I do get them. Some extra toys for the boys.

Would appreciate your honest answers.
>>
>>12876684
sexuality fluctuations are a well known effect of hormones.

it's rare for a total change to happen wherein you go from only liking females to only liking males for example, but it happens. that being said changing from heterosexual to pan/bi is extremely common in transition and is as much of an effect of the hormones as it is just becoming more comfortable in your identity and sexuality as you come into yourself from transition.

it's funny because 99% of the time the ones who use the term hon demeaningly and call other ppl fetishists are the same people who have caveman browbone and watch sissy hypnos

pot

kettle
>>
>>12885194
I don't like those anecdotes, I'm a hard trans medicalist.
>>
>>12885277
hardly any trans studies yet, anecdotes are all we have. blame the medical field
>>
do you become sterile after doing this?
>>
>>12886464
It takes a long time for sterility to happen. For sterility to occur you need both your seminiferous tubules to be completely devoid of cells and just in general a lot of testicular atrophy. It takes a long time for that to occur (easily 3+ years, likely 5+ years though).
It might take quite a long time to recover fertility once you stop, but it will probably inevitably come back. Some issues you might encounter are sperm mobility problems though.

There's always a risk of "partial" sterility in which you have sperm but it fails to fertilize. So IVF would be necessary. Most people don't ever get "full" sterility using HRT alone, especially since many get orchi's or SRS within 5 or 6 years. Maybe those on HRT without surgeries for like a decade have achieved actual true full sterility though. It's tough to say since there's really only ever been one study on it from the late 80s and they stopped tracking after 5 years.
>>
>>12883749
it happened to me as well, although I'm pretty sure it was a combination of not realizing how much of my sexuality was just raw testosterone sex drive and conflating admiration for other women looking good with attraction. (Went from 50/50 bi to like 95% men and 5% women). Either way i'd say it just shifts the ratio of whatever attractions you have right now a bit towards convention, def not like what the fetishists are imagining tho
>>
>>12886666
nice devil's quads, but keep in mind if you're doing anything where you HAVE to make sure you have sperm (mostly for sperm banking since they have to verify your sperm count), you generally only have anywhere from 3-6 months before you start running the risk of not being able to bank or something
>>
>>12886777
Of course sexuality is a deep and complex issue, but hormones on themselves won't change your sexuality, a mixture of being more secure with one's body maybe would stop people repressing certain things, but I oppose the bigoted idea that hormones change your orientation.
>>
>>12887131
https://en.wikipedia.org/wiki/Sexual_motivation_and_hormones
hormones are intrinsically tied to sexuality and attraction, why is it bigoted or even unlikely that modifying hormones would affect sexuality even the slightest bit?
>>
>>12861991
Depends on the brand. Some are half a week some are a full week. You can get a little extra out of them if you leave them on longer. You'd put the new patch on when you're supposed to, but just leave the old one on longer.
>>12863327
There's no settled opinion on optimal levels. But like the other anon said it's not enough with spiro or if going without an AA. You need 250 pg/mL to do monotherapy or spiro reliably.
>>12863792
Estrace is easier to use sublingually. That and equivalents is preferred.
>>12864141
Don't even bother with spiro if you're taking cypro. Half life is long enough to do every other day.
>>12865019
Strictly from a hair standpoint you definitely want hairs to get terminal before you stop whatever regimen you're using.
>>12865029
Progestin only BCPs won't work but the ones with ethinyl estradiol in them can work. Got to watch out for blood clots though. The dose is already low for hrt. Cutting them is not advised.
>>12865838
Doubt two weeks would do it unless you've only been on a very short time. I'd give it at least a month, and depending on how long you've been on that might not even do it.
>>12867885
You really shouldn't need to be doing that. You want to give it a month at least to get levels down. If you seriously can't get your T levels down there could be something going on you'd need checked out. But normally I'd stick with a lower dose and just give it time to work. I assume you're taking estradiol too? Cypro monotherapy could require larger doses.
>>12868565
Yes. 25 mg should be enough for almost everyone, but 12.5 is more iffy.
>>12869978
From where? Privatemdlabs it's usually within a day or two. My doctor's office can be anything from later that night to a week.
>>12870012
Up the E2 but I'd keep the cypro at 25 for now.
>>12871233
Maybe increased blood flow due to summer heat? Or the body isn't aromatizing the little T you have as much because your E2 levels are so high and it gets converted to DHT instead. Speculating.
>>
>>12872920
>>12872928
She contributes a lot of good info so I'm not too concerned with what else she does in her life.
>>12875313
You should be able to start with 25 mg. Don't go over 50.
>>12876494
HRT tends to lower your sex drive so your motivation to be "wild" might not be as great. Ymmv though.
>>12876696
You should be able to drop cypro but like the other anon says test to be sure.
>>12877260
Worst case you could die. If you don't die you could get some nasty gangrene in the genital area leading to disfigurement.
>>12877338
Spiro is only a poor tranny's version of bica in a way - it can block receptors but not nearly as well as bica. It's generally not helpful at lowering estradiol levels.
Finasteride is not the answer since it does even less.
If you can get on injections monotherapy becomes viable and you can go without an AA.
>>12877516
250 pg/mL is pretty much a sure thing for monotherapy, though some can get away with less. But you do need to test to be sure.
>>12882627
>Alberta
RIP
>>12882679
The heart condition is a concern so I'd go with doctors.
>>12882642
It's not like it's cold all year in the places where most people live.
>>12883479
>i know spiro sucks but what would a better alternative be?
Anything is better. Spiro only really acts like a weak version of bica so that would be an improvement. Estradiol monotherapy can be an option too.
>>12883526
GnRH agonists are very effective and very expensive, except for buserelin which is more reasonably priced. It's not available by prescription in the US though. And the nasal spray buserelin isn't as effective as the others that are injected or are implants.
>>12883958
Injecting every week should be better and you could probably drop the spiro.
>>12884071
You need to blood test.
>>12885167
>I thought I should take some natural menopause substance
Waste of money.
>use estrogen at a certain doses that won't give me breasts
Not really but odds are better with lower dose.
>>
>>12885167
Patches are better than pills. Bioidentical estradiol wouldn't really affect the liver that much and if taken sublingually even less so.
You can use E2 and fina together, but fina makes it harder to lower testosterone levels.
Ymmv for dick function.
Check drugbank.ca for drug interactions.
>>
Whenever I inject myself I always get a bump underneath the skin. The bump is not red.

Does this mean I fucked up my injection?
>>
Is it possible to be on patches monotherapy if i use scrotal meme? Is one patch enough for that or do i need two? Been on cypro and bica separately for like 8 months.
>>
I don’t really feel breast growth or even much sensitivity at all anymore(5-6 months HRT via injections + spiro) so should I switch to cypro?

My T is at a very low level and my E is where it should be, so I’m rather confused.
>>
Wait is it really that much more effective to inject into the butt rather than the thigh?
>>
>>12881256
Not in this thread but posted in 4 other threads and no one ever answered my questions.
>>
>>12888792
i have never gotten this and i have injected for one and a half year
sounds like you fucked up
>>
>>12888839
monotherapy with patches would likely require 3x 100mcg patches as 1 patch is roughly equal to 100pg/ml E2
>>
how much breast growth did you guys get at 8 months?
>>
>>12889245
32A/B uk sizing
>>
When I give myself injections, small, maybe a few .01 mls of estrogen seep out of the injection site, is that supposed to happen?
>>
I just got some progesterone "Utrogestan" 100mg capsules.

I've never administered anything sublingually before but I just stick it under my tongue and wait, right? Or is there something else I need to keep in mind?

The pamphlet says to swallow them but sublingual is just better, right?
>>
Can someone give me some form of hope. I'm terrified of getting Osteoporosis. What are the chances that I get it?

It makes me want to quit.
>>
>>12889245
80A
EU size btw
this is same as 75B or 70C btw
>>
I'm journey begins end of this month. I'm not going full on. I'll be taking a little less of all than most.

Looking at things realistically, how much will I change/develop in a period 5 months? Can I expect much?

I'm average built
>>
>>12889662
Sorri I no spik Engrish
>>
How are you supposed to do rectal P4? I tried but it was kind of painful and the pill came out later, I'm not sure I did it right.

Could I just take it buccally? I only hear about oral, sublingual, vaginal, and rectal P4 administration, never really seen blood results from buccal.
>>
Is it true you aren’t supposed to take EV injections alongside cypro? I think I heard something like that a while ago but idk.
>>
>>12847289
Will ev injections do anything for my hair? I don't have any male pattern baldness, but it's been thinning everywhere for years now, and I'm wondering if it will get better when I start them.
>>
>>12889823
Get Finasteride quick, thinning hair is the equivalent of male baldness.. And eat healthy. Also be careful with Finasteride because it makes you go limb sexually. Unless you don't care.
>>
>>12889841
Hmm. I'll have to think about it. Without going into detail, I really don't think I'm balding. I just have the male equivalent of my mother's extremely thin, frail hair. Would only finasteride help with that?
>>
>>12890066
You have DUPA, or diffuse unpatterned alopecia.

DUPA can be caused by androgens, hence you should get on an AA/estrogen asap to stop it progressing further. No guarantees it will fix the problem but it's better than doing nothing and watching your hair thin into nothing and your transition suffer as a result
>>
>>12890087
Yeah he doesn't want to look like smeagol at the end of the day.
>>
>>12890087
That could be possible. None of the pictures of it look like my hair (visibly, it looks normal (pretty, according to a lot of people)), but it's not outside the realm of possibilities. I just finished my three month starter dose of e sublingual and Bica, and I'm moving on to e2 monotherapy, so don't have to worry about that, at least.
>>
>>12847289
>▶ Breast development info: https://genderanalysis.net/resources/studies-on-trans-womens-breast-development/
this link is dead btw.
>>
>>12847289
What are doctors supposed to test for to measure how well Bica is working? I know it's not T, but I can't remember what it is.
>>
Are patches ideal for the patient transitioner?

I can't do injections.
>>
>>12888857
How is your growth for info? I would try switching to 100ug patches for a while, since you are taking AA.
>>
i've been on 25mg cyproterone and 2mg estrofemme for 8 months now.
I just got results from bloodwork i had a few months back turns out my prolactin was at 43.475 ng/ml.
That's pretty high, should i be worried?
>>
>>12889662
You will probably get breast buds but that's it
>>
>>12890639
So with HRT and exercise my body won't change a little feminon wise?
>>
>>12890681
Probably not, 5 months is nothing
>>
>>12890681
If you are a zoomer like me you might get some hip growth, or atleast the pain.
>>
should i be worried if my injection fluid is turning yellowish? using two lena vials for reference
>>
I've been getting more erections since I started bica, should I be worried?
>>
I'm a dyslexic non-english speaker with a below-average IQ. Can someone pls translate the results of this study into simple language for me
>https://academic.oup.com/qjmed/article/110/11/729/3869105
Is eating less or more frequently better for maximizing subcutaneous fat? Is eating few large meals better than several small?
>>
>>12891229
High EF is associated with lower progression rate of pre-peritoneal fat accumulation.

eating more often = less fat around your organs, if im reading this right.
>>
>>12891257
Thank you anon
>>
>>12890354
patches > pills
>>
most of my deltoid shots have been practically bloodless, got several droplets pulling out this time tho
what does it mean?
>>
>>12891848
I'm mostly asking cause there's been like no blood so I wonder if I injected wrong and wasted it more than anything
the blood doesn't scare me really
>>
can cyproterone actually permanently decrease testosterone production so I can switch from cypro to spiro after a couple months on it without raising levels or not?
spiro seems like sugar pills but androcur is $100 for like 50pills.
>>
>>12892379
It could take years and it's a ymmv thing.
>>12890999
That's to be expected since a feature of bica is less effect on erectile function than the alternatives.
>>12890958
How old are the vials? I can't give you an answer but that doesn't sound good.
>>12890425
It's higher than it should be but not at a panic level. If you could cut back on cypro that can help. I'm surprised you haven't upped your estrofem dose yet. But if you increase that without lowering cypro that could aggravate the prolactin problem.
>>12890354
You can definitely get good results from patches.
>>12890343
PSA test.
>>12890202
I guess a review of links is in order.
>>12889773
You can do it, but with injections it's easiest to do monotherapy where you don't even need an AA. The biggest concern for injections+cypro would be elevated prolactin levels I believe.
>>12889393
Osteoporosis should only be a problem if you're on an AA only regimen. Estradiol is protective. It's when both estradiol and testosterone are low that you get issues.
>>12889322
That is micronized progesterone. I don't have experience with sublingual progesterone personally, but I imagine it's like with estradiol, where you have to wait for it do dissolve completely. You should avoid eating or drinking anything for about 15 minutes afterwards, and try not to swallow before it dissolves. Sublingual is better for progesterone and estradiol than swallowing.
>>12889321
A little seepage is common. Be sure to move injection sites around so scar tissue doesn't build up.
>>12889245
About an A cup.
>>12889023
I try to answer unanswered questions but I've been a lot busier lately irl and haven't been able to follow the threads as closely as in past months.
>>12885167
It looks like olanzapine has metabolic interactions with estradiol, cypro, and bica which can affect the doses needed. Doesn't look major. Ritalin can lower estradiol excretion and spiro can increase ritalin secretion and ritalin can lower efficacy of epilim and ozpine
>>
>>12887806
>>12887700
>>12892503
good poster(s)
>>
Is starting hrt at 25 really just a meme? Am I a lost cause and should I give up? I've heard that even with ffs I still won't pass at all. Please, I need to know the truth.
>>
>>12892637
at that point your bones are fucked, you can still take hrt and get thinner skin and lighter hair, but you are a lost case, don't get hugboxed into believing otherwise.
>>
>>12892637
depends where you're starting from. only if you're small framed / andro you will have a chance. and ofcourse ffs and maybe more surgeries. you can always just medically transition, but not socially if you're thinking you won't make it. Still better than getting more manly

>>12892662
come on, not a lost case, chances are ofcourse worse the later one starts, but a few lucky people still make it.
>>
>>12892698
>>12892662
Are there any examples of people transitioning at this age?
>>>/b/804573000
link to /b/ because it's nsfw, but this is my body. I'm hoping that there is hope since ymmv is a factor here I think.
>>
>>12892783
Body looks promising, but the face can break you of course. And there's no way to know what kind of boob growth you'll get.
>>12892321
Highly unlikely it's wasted as long as you make it at least to the subcutaneous layer. At that point the big problem would be injecting into a vein which would be a waste. But if that happened you could expect to see decent amounts of blood.
Injecting into a vein is a waste because blood levels would spike super high really quickly, but then be metabolized away within a few hours.
>>
>>12893095
>But if that happened you could expect to see decent amounts of blood.
Ok but, how much is "decent"? I went from basically no blood to enough to form drops that smudged my arm.
>>
>>12893100
>>12893095

Drops plural, I had to keep dabbing them away for a few moments to keep them from running.
>>
>>12893100
You might have pricked a vein. Blood draws in my experience don't usually cause more bleeding than you're mentioning. The main way to check whether you're injecting into a vein is to pull back on the plunger a bit and see if blood gets drawn into the syringe. Apparently there is some risk of an oil embolism when oils get injected into the bloodstream. If you didn't notice any unusual reaction to the injection you might have just nicked a vein. And I'm guessing that given the size of the veins in the area and the angle of injection it's very unlikely that all of the injection would go into a vein even if you hit one.
>>
Where do you do injections in the thigh? I've only ever done them around the belly button but I think I want to start using my thighs
>>
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>>12893585
Here are common injection sites.
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>>12893629
thanks!
>>
New thread:
>>12893746
>>12893746
>>12893746
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>>12892783
I just realized I don't take many pictures from the neck up but here is a fairly recent one within... I dunno the last month. Thread is dying anyway and I'm not too scared of public laughter. It's the internet.
Boobs I dunno. I don't even know how/if it works with someone at 25+
Though these are things that, technically, surgery can fix, right?
>>
>>12893777
meant for >>12893095



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