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>Help, advice, guidance on medications and dosages
>HRT related medical experiences and research
>Availability and pricing of medications
>Rational and scientific discussion

Please take the survey and help us determine the best medications, dosages, and treatment regime to get the results we want.
See the first post for a pharmacy list.

▶ Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Raw survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Anime Girl Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill Identification: https://www.drugs.com/imprints.php
▶ DrugBank Database: https://www.drugbank.ca/
▶ Basic HRT info: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ HRT target ranges: http://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Endocrine Society guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Callen-Lorde Guidelines (with flutamide): http://callen-lorde.org/graphics/2018/05/Callen-Lorde-TGNC-Hormone-Therapy-Protocols-2018.pdf
▶ WPATH SOC: https://www.wpath.org/publications/soc
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Breast development info: https://genderanalysis.net/resources/studies-on-trans-womens-breast-development/
▶ Blood testing (US Only): https://www.privatemdlabs.com/
▶ Blood testing (UK, Ireland): https://www.medichecks.com/
▶ Blood testing (Canada Only): https://bloodtestscanada.com/
▶ Blood testing By Mail: https://www.letsgetchecked.com/ - DIY capillary blood samples. Expensive.
▶ Lab test guide (reference ranges): https://www.healthcare.uiowa.edu/path_handbook/index.html
▶ FtM HRT guide: http://www.ftmguide.org/ttypes.html
▶ /HRTGen/ Archives: https://1drv.ms/w/s!AudRJceTA5C9fiPMDzSLX7xF9MI
▶ More Archives: List at 8ch /tttt/ HRT Info Dump sticky
Previous thread: >>12631968
>>
The online pharmacy list:
inhousepharmacy.vu has been popular in the US.
eu-aibolit.com is a reliable site that ships to a lot of places. Good for EU anons. They list shipping rates for the UK, Canada, and US among others so I guess they ship there. http://eu-aibolit.com/content/15-usloviya-dostavki
shesalady.co.uk reportedly ships to Canada. You need to email the site operator to order. In the EU shipping times of two weeks have been reported. Email contact@shesalady.co.uk to order.
unitedpharmacies-uk.md seems to work for the UK.
There's also unitedpharmacies.md (US-centric) and unitedpharmacies.nl (Netherlands-centric)
alldaychemist.com is another.
http://lena.kiev.ua/ev/ has become popular for injections.
Less reliable/untested/poorly tested sites:
https://inhome-health.com/ seems iffy so consider them a last resort. Messed up orders have been reported. They are said to ship to Canada.
http://fast-pharmacy.com/product/Evista.html has raloxifene and some other meds but is expensive.
Possible source of a reasonably priced GnRH agonist: http://cherrypharmacy.com/product/buserelin-nasal-spray-analog-suprecur-suprefact-nasal-buserelin-acetate-150-mcgdose-180-doses/
https://amazon4health.com/ - expensive, no bica.
https://shape-shifters-eu.netlify.com has some satisfied customers.
I saw www.buyonlineventolin.com mentioned in a thread but I have know idea if they're reliable or not.
>>
I think there are less painful ways to kill yourself
>>
Trying to ask and possibly shill if anyone wants my injectables without ethyl oleate since some anons voiced concern for Lena's.

>>12676439
Search up Nembutal
>>
My doctor just told me that my E was too high (800pmol/L) because it isn't in the EU regulations range, which is something like 350 to 750 pmol/L.

Her solution to this is to halve my dosage. Given my last few blood tests with various dosages, halving it now would probably put me at about 400pmol/L.

Is this the part where I go on DIY injections? I thought if I could stay at 800 then going with the legit route would be safer and more reliable long term, but if I'm getting shoved down to 400 then what am I even supposed to do? Is there even an option?

I've asked the doctor so many times to let me do monotherapy and that's apparently a no-go. So are injections. I'm still baffled that 800 is too high.
>>
How do I keep patches on the entire week? At least one of them always gets a fold that lets shower water in, is there something I can put over them? Should I take some the sublingual E I still have when one or two of them come off too soon?
>>
I've been on Finasteride for 6 months, but hrt for 2.

I've got 2 weeks supply of Fina left, but I take cypro as my AA. Should I restock on Fina, or am I ok to just stop Fina when it comes to an end?
>>
>>12676573
Yes. That's WPATH ranges and it'll make you a hon. 250 pg/mL before next dose or BTFO.
>>
>>12676632
Injections it is then. Still terrified of injections and I'm very pain sensitive, but it really doesn't look like I've got any other option.

At least I'm a late transitioner and I'm already a twinkhon though. Is that a bright side?

Also need to get sperm samples in 3 weeks so I'm going off HRT until then, this is extremely stressful.
>>
>>12676710
Huh

If you like use 24-25 ga needles after you got over the anxiety it makes you wonder if nurses do it wrong because it is relatively painless.
>>
threadly reminder that spiro and pills are both for hons
>>
>>12676738
I just mailed lena to try and figure out what to do. Anxiety or not, I can't keep doing things the legit way.

Where can I get needles? I have no clue about needles and injections in general so I don't really know what to look for. I've been told to find a needle exchange in my city but there doesn't seem to be one. Lena site says to use insulin syringes, can those just be bought online or something? I'd assume they're one-time use... But one every 2 weeks is probably not too expensive I guess.

Damn I wish healthcare was less regulated. I wish I could just go to the hospital where I get blood tests and ask the nurse "Hey teach me how to do that" and they could just say okay. I guess with fewer regulations I could also just keep doing legit transdermal and be fine too. But fuck it, this is where we are now.
>>
How do patches work? Like what's a suitable dosage and how does showering work with them on?
>>
>Always very skinny growing up, 28 inch waist
>Get on E a few years ago
>Fat starts going to belly
>32 inch waist
>blood test levels are great

female fat distribution they said
it'll go to your thighs and ass they said
>>
>>12676574
>>12676826
Some info on this would be great
>>
>>12676790
Threadly reminder that you should only on shots.
>>12676816
Yeah me too. Are you at a shit place or not?
>>
>>12676830
females can have fat bellies I say
>>
>>12676880
Being denied proper medication by my doctor is a fairly shit place, I'd say. Unless you're asking about my country. Denmark's nice and healthcare is good in other areas (and free), but again, regulations mean it's not worth it which is kind of shit.
>>
>>12676830
How old are you?
>>
>>12676960
proper medication: the current trend of teenagers on an anonymous image board
>>
>>12676830
You're not on spiro are you? Spiro causes belly fat and fat around organs due to elevated cortisol.
>>
>>12677020
My doctor doesn't understand the difference between peak and trough levels. She also doesn't understand the difference between applying transdermal medication to the arm, and to the scrotum (despite me explaining it every time we've talked).

Regardless of how unreliable the internet is, the doctor is not worthwhile.
>>
>>12676426
can anyone here vouch for united pharmacies uk?

I'm desperate to get on hrt but I've heard horror stories of people somehow having their accounts emptied after using them, or at the least packages not arriving

can anyone give me advice on what to do? or any other good sites to order to the uk?
>>
>>12676830
YMMV
>>
>>12677058
> doesn't understand the difference between peak and trough levels
Really scary if true. Sure it's not just a misunderstanding?
> difference between applying transdermal medication to the arm, and to the scrotum
So give her the information she needs as a professional? If you can find any that is, I only find some papers about scrotal testosterone and E isn't testosterone.
>>
>>12677085
I live in the UK and use United pharmacies and have never had an issue with them
>>
>>12676960
buy online. if you can buy syringes/needles smaller than 100 pcs, do it. for needles, buy 23 ga 1"
>>
Has anyone tried injecting alcohol into their testicles to get them removed yet? I'm having surgery soon so it'd be a bad idea for me to do it right now, but I'm curious if it's a good idea for later
>>
>>12677145
ah that's great to hear!
did they make you do a wire transfer for your first payment ? how much did that end up costing you, and how long did things take to arrive?
>>
How the FUCK do I take my sublingual pill between my cheek and teeth? I had it in for an hour until it just got everywhere in my mouth rather than be absorbed.
>>
>>12677129
>Really scary if true. Sure it's not just a misunderstanding?
I really hope so, but I'm not sure. I asked her a few times about trough levels and she basically ignored the questions, and she's never told me, for example, when I should get tests. I once told her that I'd taken sublingual pills before coming to the appointment, and she said it's fine and that I should get a blood test immediately anyway. I don't think she knows.

>So give her the information she needs as a professional? If you can find any that is, I only find some papers about scrotal testosterone and E isn't testosterone.
I compiled a few different papers about it and showed her several meetings ago. It's true, only one of them was for E (https://docs.google.com/document/d/1dteNhG9wewvNX5zj0YcXrVAuQFZdtcqWmUWVvgI5uKs/view), and the rest were for T. I discussed this with her, thinking she'd be like "Wow this is great, we should test this and see if it works because it'll save so much money" but she just said "Okay try it if you want". And she seems to have forgotten about it now.

I talked with her this morning and she said "You're very sensitive to the medication so that's good", despite my levels being horrible on her recommended dosage prior to scrotal application (I was at 250pmol/L on 3mg), showing that I'm actually quite unreceptive to E. On pills, I had to take 6mg sublingual to get 600pmol/L. This is not "very sensitive to the medication".

But of course, she doesn't remember or care about any of that, so she thinks that the scrotal application's success is just due to me being an estrogen sponge. Despite me reminding her literally. LITERALLY. Every time we discuss my blood tests.

I get that I'm just one patient out of about 500, but this is still unacceptable to me. I'm going back on DIY.
>>
>>12677176
Any reason for saying 23G? I'm new to needles but as far as I can tell, bigger gauge = thinner needle? In my mind, thinner needle means less pain, but I guess that's not necessarily true.

Based on what I can see at my pharmacy, my choices for syringes are mostly 29G with a few that don't say what they are. The 29G ones are 12.7mm, which should be fine.
>>
How necessary is a DHT blocker when you're on an AA?

I keep getting conflicting responses
>>
>>12677305
No I just paid by card I always have. Things usually take a week and a half to two weeks to arrive
>>
>>12677535
I've been asking the same question for the last few editions, and I've gotten no response.
I've kept taking Fina after starting hrt, but I'm coming to an end to my Fina supply, and I'm not sure if I should restock, or if I'm fine.
>>
>>12677520
i just googled this, and generally speaking, for IM the higher gauge the better, unless the fluid you're injecting is thick, warranting a thicker needle
im using 21G needles for my valerate injections, seems to work just fine
>>
>>12677626
I've panic bought some Dutasteride but now I have no idea to take it or not. Been rambling about this multiple times now but the initial hair shedding of fina/duta terrifies me and I don't want to put myself through that anxiety or have the additional strain on my body is there's no benefit to it
>>
>>12677626
if you're on cypro it shouldn't be needed as there won't be any T to convert to DHT to begin with
>>
>>12677699
Thank you, I will personally have sex with you for answering this for us

Can anyone vouch for HRTs efficacy in preventing hair loss etc? I am fairly sure I am not experiencing hair loss, actually having some slight growth I think, but it is something deeply concerning for me and making me very stressed and upset
>>
>>12677699
I am on cypro.... so I think I'll just take the last of the finasteride and then when I run out, I run out. I have like 2 weeks left anyway.
>>12677676
I got a bit of shock hair loss when I first started finasteride, but that lasted a week for me, and the hair just grew back. Overall, I my hair has improved from the balding I did have. It's still not perfect/where I want it to be, but I understand it takes time. The area which is thinner is now a lot smaller, so I'm optimistic for more progress.
>>
>>12677637
I'll just go with the 29G then, since that's easiest to get.
>>
>>12677733
>>12677736
HRT will stop and might reverse hair loss caused by male pattern baldness
there might be other causes for hair loss though that HRT will do nothing to prevent
>>
>>12677797
I had (have) an eating disorder and seem to have some skin condition like psoriasis on my scalp so I'll bet its either of them

Thanks anyway, I felt so bad and you've really brightened my day
>>
>>12677797
I've already noticed it start to reverse on finasteride.
I know about stress related hairloss, but as far as I know, that's far more temporary.
>>
>>12677808
>Thanks anyway, I felt so bad and you've really brightened my day
im very glad to hear that, you're welcome
>>
>>12676826
Patches will give you 1 pg/ml for each 1ug. 100ug patch should give around 100pg/ml levels.

Anyone tried 1mg injection for not so high levels?
>>
>>12677955
>>12676826
not 100% true, usually it does that, but for me a single 100ug patch = gives me 68pg/ml E2 levels, and the scrotal meme doesn't work for me, so I have to wear 3 at a time.

make sure to always test your blood
>>
nothing wrong with keeping 3.5 day patches on for an entire week in order to get the maximum amount of estrogen from it right?
>>
I want to start DIY with Baci , im 23 , 6ft , and 150lbs. How would i calculate dosages?
>>
>>12677409
Even if you are 1 out of 1000 she should have notes to read before meeting you, this is just unacceptable. Is it possible changing to someone else?
>>
>>12678216
I don't think I have other options in my city. She's the specialist trans stuff doctor, separate from other doctors. My current plan is to switch to DIY injections, and try to convince my regular doctor to give me blood tests every once in a while.

My previous regular doctor had no clue about trans stuff, but I told him I needed blood tests, and what to test for, and he was like uh okay and signed me up for one. Haven't met the new one yet (I moved recently), but hopefully she'll do the same.

>>12678014
What do you mean scrotal doesn't work for you? Are you sure you're applying them correctly? I'm just curious because scrotal has worked great for me (200->800pmol/L same dose), and I'm interested to learn what might cause it to fail.
>>
>>12678263
>What do you mean scrotal doesn't work for you? Are you sure you're applying them correctly? I'm just curious because scrotal has worked great for me (200->800pmol/L same dose), and I'm interested to learn what might cause it to fail.

I don't know. I plucked the area of application, exfoliated it, cleaned it with alcohol, dried it with a clean sheet, applied the patch while the skin was stretched as much as possible and then held it down it with tegaderm, and it gave me the same levels as before, Feels bad gang.

The only thing I think that could've caused it to fail was that there wasn't much space on my scrotum so I had to use the same area with only a 3.5 day break, but I was cleaning the area vigorously so it shouldn't have been a problem, right?

Scrotal patches work because the area on scrotal skin is supposed to be thiner than most other skin on the body, I guess my scrotal skin could be unusually thick or something.

An alternative to microneedling that I would've tried had I not moved onto injection would've been microneedling of application to increase bloodflow, some anon here said it worked amazingly for her.
>>
Does it matter which estrogen I buy? I've been taking Estrofem but quite frankly It's expensive and I can't afford to take more than 2mg a day.
>>
How long does it take for cypro to take effect? I started last week on Tuesday and my ejaculate is still white.
>>
>>12677955
i get 342pg/mL from 1x 100ug patch
on my inner thigh not my balls
>>
>>12678308
That sucks. I don't know much about patches, but I use a transdermal spray on my scrotum and it works without any of that cleaning or stretching. I just put it on and it works. I don't think using the same area repeatedly should be a problem. I use the same spot twice a day with my stuff and it's fine.

I wonder if it's the stretching that could have caused the problem. Like, maybe stretching the skin too much makes it less receptive to E... I dunno.
>>
>>12678486
>maybe stretching the skin too much makes it less receptive to E... I dunno.

I don't know, the skin doesn't look scarred, and I strech the skin to get as much surface area as possible.

Sigh... yeah I'm upset it didn't work for me. Ohwell, atleast I have injections now.
>>
Can I take the prometrium gel capsule sublingually or rectally?
>>
>spend good money investing in injections because they give so much "good" estrogen
>not even sure if it's working as well as my last go with sublingual
am I crazy
>>
>>12676574
>>12676826
>is there something I can put over them?
Tegaderm. Works like a charm
>Should I take some the sublingual E I still have when one or two of them come off too soon?
couldn't hurt

>>12678415
It should already be taking effect. Give it a few more weeks and you'll notice a difference. How high is your dose btw?

>>12678991
Why don't you think it's working?
>>
i was reading an archive of the transgirl thread and saw a chilean girl crying over hormones, i dont know how to contact you little crying girl buy you can but Espiro and Primaquin at drugstores without recipe, I know because I have a recipe and never use it.
i hope you read this, also if you need help w anything contact me on kik (frantrans) or leave your whatever and i talk to you
>>
btw does anyone here have experience with taking sertraline(anti-depressant) and HRT at the same time? Does it interfere?
>>
i have a hard time doing deep I.M. injections but they make me look and feel so much better than i do when i’m on tabs. Any other trans girls wanna share their experiences with patches, cream, subcutaneous injections? really desperate for anything
>>
>>12679030
Thanks! My dose is 25mg.
>>
>>12679090
25mg is good. During the first month i noticed my sperm becoming clear, and now after 2 and 1/2 months I almost don't shoot out anything and have difficulty maintaining an erection.
>>
>>12679104
I read on /r/transDIY that 12.5 should be enough as a maintenance dose when your T is tanked. Have you tried that?
>>
>>12679126
nope
>>
>>12678069
It might cause a skin irritation. Did for me, so now I'm back to only leaving them on for 3-4 days.
>>
should i cut my e dose if my e is 350 pgml
>>
>>12678115
Dosage of bica should be based on circulating T level, not body mass. I forget the ratio of ng/dl blocked for each mg of bicalutamide, though. The half life is quite long, so the blockade should increase in efficacy over time, up to a point.
>>
>>12678933
Yes. But I've never observed any data to show how efficacious sublingual is vs rectal.
>>
>>12678263
Practicing doctors are not the same as clinical doctors. She's likely not particularly interested in random research articles since it's not what her job entails.
She would get her info from compiled guidelines since a lot of clinical research never actually makes it into common practice.

It sucks when your doctor doesn't care much about trans stuff but really most doctors just follow along generic guideline documents because most aren't interested in trans stuff they're just doing it for money.
>>
>>12677520
>>12677637
>>12677791
Yeah, it's not obvious, but Lena's (and my brew too) uses castor oil, which is considerably thicker in consistency. Now Lena's use ethyl oleate, where I use benzyl benzoate instead, so I don't know the actual viscosity for Lena's brew, but in my experience, I would desire just a size or two up because it takes forever to administer. Then again I use 5 mL syringes which is not optimal when you only administer 0.6 mL.

Also, 23 ga (at least from the folks over /r/steroids says), is pretty safe to not fragment the vial's rubber stopper.

Higher gauge will cause the oil to flow slowly, and combined with large syringe it could be a pain to administer.
>>
Someone told me fenugreek would help me with producing milk? Is that true? It sounds like bs.
>>
>>12679126
I started on 12.5 and my cum is clear.
>>
>>12680877
There have been reports of very high fennugreek intakes causing hyperprolactinemia so it's possible. It's not healthy though and it's a cancer risk.
>>
>>12676790
thanks almost forgot
>>
>>12678374
inject lena dust my dudette
>>
>>12679061
https://moderntranshormones.com/2017/11/01/subcutaneous-injection-of-hormones/
just don't inject as deep and that's literally it
>>
>>12680877
take domperidone instead
https://en.wikipedia.org/wiki/Domperidone#Lactation
look it up
should be on IHP
>>
>>12676830
keto
>>
>>12677370
What pill? If it has a hard shell like progynova it helps to crack the shell open first to let the powder dissolve
>>
>>12676573
There is no proof that high E2 levels lead to more rapid feminization. There is however proof that when E levels are too high breast growth is stunted. A big reason why lots of tranners are itty bitty titty is because they have the "ogaa bogga more is better" mindset

>>12676632
Retard.
250 pg\ml is the peak E level that the average cis female reaches during ovulation. It only spikes this high for 3 to 4 days.

The average range people should aim for is 300 too 500 pmol/L of E2.
>>
>>12682715
>There is however proof that when E levels are too high breast growth is stunted.
There's only anecdotal evidence for that.

It doesn't explain why cis females that take ethinyl estradiol in BC get breast growth (35ug of EE is essentially 3.5mg oral E2). So they have massive estrogen levels and can get breast growth long past puberty ends.
>>
>>12682715
There's this doctor who has the name of Dr. Will Powers. He said to mainain 250 pg/ml at all times.

I'm curious of which dose is actually the optimal dose. Too bad I'm not a clinical doctor or a researcher.
>>
>>12682715
>There is no proof that high E2 levels lead to more rapid feminization.
This is not the only reason to aim for high E. All the easily obtainable AAs are bad for their own reasons, and E monotherapy lets you not need them. I'm also 2 years into HRT on hon levels so it's not like I'm interested in "rapid feminization".

>>12682894
I'm pretty sure you can find a doctor that'll confirm any "fact" at this point. I can easily find doctors that say 100pg/mL is perfectly acceptable, and I'm sure there are some who advise above 300pg/mL for monotherapy reasons.

Medical science is hard. Different people require different things. It's too early in the field of tranny science to say for sure about any of this stuff.

Scrotal E looks very effective but maybe it causes cancer. We can't know until people try it for decades with observation. Maybe high E causes breast cancer or some other problems. Maybe it doesn't. We're all just trying our best to figure out what works, at this point it's mostly tiny sample sizes or anecdotes.
>>
>>12682715
>:
The research I've seen seems to indicate that the reason breasts so seldom fill out completely is that they cycle isn't actually mimicked; its a dual wave of progesterone and estradiol out of phase, and mimicking that cycle would bring superior results.
>>
why is injecting in belly fat meant to be better than in the deltoid?
>>
>>12683066
Links? Most breast growth occurs during puberty, before estrogen/progesterone levels start cycling. I'm pretty sure inadequate breast development is mainly due to people transitioning after puberty, which means the size of an AMAB's skeleton will be larger (causing the breast tissue to be more spread out), and levels of HGH/IGF-1 will be substantially lower.
>>
>>12683071
it's easier to do by yourself and less chance of hitting nerves/blood vessels/connective tissue/etc
>>
>>12676557
>without ethyl oleate since some anons voiced concern for Lena's.

What's wrong with Lena's? Went through the last few threads and didn't find anyone mentioning it besides you
>>
>You want the lowest dose of E that works (i.e. puts u at a healthy spot in the cis female range), cause that allows more time for potential bone growth, and better breast growth. Also lowers health risks.

What did they mean more time?
>>
>>12684442
Think it has to do with the redditor who supposedly found dust particles in a vial, although that redditor later realized they were wrong
>>
>>12684554
I'm sure some linked a paper but TL;DR EO is bad but IDK for what reason.

Not that I care though.
But from hearsay it allows for more actige ingredients to be disolved in the same amount of oil.
>>
if breast growth is 'stunted' does this mean it happens slower or just will never happen after? from what ive read in this thread my e is too high so im gonna cut down to a 50 ug patch..
since i only have 100 ug patches atm would i be able to cut the patches in half? or is this dumb for some reason?
thx x
>>
>>12684665
idk my e levels were really high at frst but when I reduced by just 50 my levels went too high and my breast growth has been complete garbage ever since desu

I hope lena's magic injections will save me still
>>
>>12684868
wait... you levels were too high, you reduced and they went to high?
so now you want injections which give you mostly high levels?
im so confused
>>
>>12684876
OH sorry. I fucked up.

They went too low after I reduced the dosage. Like literally from 1700 on 200ug to 170 on 150ug. I upped back to 200 again but no idea what levels are now since am between blood tests. But my boobs arent doing anything at all.

I want injections both for better levels and because sometimes people report getting better results on injections even with same levels.
>>
im also confused because I keep reading lower levels are better but injections definitely give you days of high estrogen, but they're supposed to be better
>>
Is 0.44ml EEn every 2 weeks safe? The peak level with that dosage sounds like it would be very very high. Would smaller doses every week or 10 days be safer?
>>
Somebody tell me where to buy 50mg cypro tabs so i can leave this website forever. Thanks.
>>
how do am I supposed to dose my estradiol using gel? if one application gives me 1.5mg and i want ~6 in a day, should i apply 2 on each arm bidaily?
>>
>>12685678
inhousepharmacy. been ordering it for almost a year no problems.
>>
>>12678428
which patch do you use?
>>
>>12686001
dermestril from shesalady
>>
Thinking on giving patches a go

Is 100mg a good dosage? And how does showering etc work with them?
>>
>>12686366
>Is 100mg a good dosage?

Some get by with 100mcg, most need 200mcg, I needed 300mcg, it depends on your skin.

>And how does showering etc work with them?
Look up Opsite Flexifit or Tegaderm, they super thin adhesive adhesive "stickers" that hold them to your skin.
>>
Decided to detransition and quitting HRT today after 2 and 1/2 months. Fingers crossed my penis starts working properly again, and semen returns.
>>
>>12676424

I'm trying to get myself hiperkalemia, any tips?
>>
Hello, does anyone know whether crushing E for sublingual decreases its efficacy? Medical websites keep telling me crushing pills can alter the way they work, but none of them explain why.

I've been taking estrofem 6mg sublingually for a while and getting good results, but each pill takes 30-40mins to fully dissolve, which I can't see myself doing for the rest of my life. I live in the UK so no injectable estrogen here AFAIK.

Thank you for any help or links to info! <3
>>
>>12686642
What all changed in you from the 2.5 months of hormones?
>>
>>12688251
Here's why. sometimes a pill is coated to alter the way they release into the bloodstream. by crushing them, you destroy the pill and whatever release mechanism in place, and instead you will get a short spike instead. (also crushing them=bigger surface area Efficiency wise it doesn't really mattery, but it changes the release pattern
>>
>>12688251
multiple layers of pill + longer duration of absorption.
if you crush it,you get all of the pill at once, which gives a different affect than intended
>>
>>12688251
I chew my pills and I've had way better results than trying to dissolve it fully intact.
Coatings are designed to alter intestinal absorption so it shouldn't be a big deal. As far as estrogen goes it does not degrade in stomach acids so the coating really doesn't matter anyway.
>>
What is the appropriate dose of cypro for someone who was on spiro for 2.5 years
>>
>>12686383
I need 400 mcg because I'm a skinhon.
>>
>>12686383
Are there any patches available in 200mcg? Because if I'm having to use two patches at once it will get very expensive
>>
>>12684900
ancient entrenched big pharma propaganda vs overwhelming anecdotal evidence

>>12685486
yes it's safe

>>12688954
25mg is standard to start with. if your E is high enough you can reduce the dose or drop cypro completely
>>
>>12688257
You mean physically? I think I developed tiny little boobs but they're hardly visible and will probably go away if I loose weight. Other than that I got more emotional and less aggressive.
>>
>>12688954
why? do you want to be suicidally depressed 10 times more?
>>
>>12688251
>no injectable estrogen here
just buy it from lena, it's worth it
>>
>>12690775
fuck off lena
>>
>>12690792
reminder that the person claiming to have particulates in their vials admited that they were mistaken

https://www.reddit.com/r/TransDIY/comments/bxhu6l/update_on_dust_in_injectable_vial_i_was_wrong/
>>
>>12690818
probably paid by lena to say so.
>>
>>12690792
her prices are very competitive tbhon
i paid 80 USD for 10 vials of 10mg/ml containing 1ml of estradiol valerate OTC in thailand
10 vials is 50-70 days worth of EV
meanwhile lena's juice will last you at least 6 months for cheaper
safe to say i got scammed and should have just bought lena's juice instead of risking all my vials taking them through customs (i bought a total of 50 vials)
>>
>>12690818
Reminder you should be using filter needles to draw from anyway to avoid any potential risk, then swap to the finer injection needle.
>>
Normally after injecting in my stomach i get a lump under the skin that goes away after like 2 or 3 days but on my last injection its still there after a week, did i fuck up the last injection or something?
>>
>>12676424
heya, I'm sorta new to all of this stuff sorry :( Can someone tell me about the different types of pills pls? I know about regular estrogen promoting stuffs, and anti-androgens are meant to reduce masculine traits such as hair and redistribute fat without promoting female traits right? Are there any others? Thank u for any answers <3
>>
>>12693908
are you actually this retarded? you have two sex hormones in your body, estrogen and testosterone, you can probably guess what they each do. estrogen pills just gives you estrogen since you dont have ovaries to produce it while aas limit your testosterone
>>
>got bottom surgery last year
>still feel a sense of discomfort and like there's something wrong
>only just clicked on that this might be true dysphoria unlike what I was experiencing before
>starting to miss my penis and constantly worry about how my frozen sperm might not work when I decide to have a child
>can't stop having nightmares about how I'll never be able to go back
>can't stop worrying about better surgeries and alternatives being released in the future whilst I'll be stuck feeling dysphoria over a closing up wound
>grandfather gave up his cancer treatment so I could have this and now he's dead and my only living parent won't talk to me anymore after I brought this up to them
I can't take it anymore...
>>
Are there any benefits to cycling progesterone? Seems counterproductive to just stop taking it sometimes.
>>
>>12694027
I think you posted on the wrong thread lad
>>
This is probably a dumb question, I'm kinda new, but is cypro supposed to be taken sublingually or by swallowing? which is better?
>>
>>12694794
Swallowing. Sublingual is only a thing with E pills.
>>
Can someone explain anti-androgens please? I've been told they redistribute fat, but I assume that's wrong information and that they were actually talking about E.
>>
>>12677217
Do not do that
>>
>>12694794
It's a suppository
>>
>>12697209
AA block testosterone and depending on the AA, prevents testosterone production. Testosterone masculinizes you and prevents estrogen from working properly, so AAs stop you from masculinzing and allows the E to work

E does everyhing, from making your skin softer, to giving your boobs to causing fat redistrubtion

In some cases just taking an AA is enough to cause some of these changes, but usally much less potent and slower than if you take an E as well.
>>
Hey you all
like ok I get it can anyone pleasee explain me what's the difference between cypro 12.5 and 25 mg. thanks! :) (i got a shitty gnrh analogue and it's still affecting me 2 months later deespite 12.5 mg cypro should i up this shit???)
>>
>>12697703
ooo, thanks for the info. Apparently one of the AAs stands out at fat redist and skin smoothing. Do you know which one? :)
>>
>>12697723
There's no shitty grnh analogues. They are all the gold standard for AA, if it comes in injections, even more effective than cypro.

>>12697857
cypro I guess?
>>
>>12697857
I heard someone say that sprio gives you clear skin, no idea why though, as far as I know all AAs reduce testosterone would therefore make faces less oily and therefore more clear. It certainly doesn't help with fat redistribution either given that it promotes fat to build up on the belly
>>
>>12698024
Tvym hunni, I'll look into cypro :)))
>>
>>12698024
>There's no shitty grnh analogues
you think so? check out buserelin russian nasal spray. you're lucky if you haven't died.
>>
>>12698063
>if it comes in injections
try again.
>>
How bad is it to stop HRT for 3-4 weeks?

I didn't have a chance to save sperm pre-HRT, and now I have a chance to do it for free (start of next month). I stopped HRT last week to try and have a chance at maybe producing sperm by then. It's hopeful, I know.

Already feeling the T really hard. I'm all greasy and covered in acne, it's gross. I'm 2 years HRT, could a month at this point have permanent consequences?
>>
>>12698156
>There's no shitty grnh analogues
>Gold standard injections
sukk my pickle
>>
>>12698214
I don't know what you're talking about, but this made me giggle :^)
>>
>>12698063
Buserelin is used in Canada as well and it works fine.
>>
>>12698256
where is it produced? Russian ones prove to be awful, at least 1 of 2. People struggle with this shit after months of discontinuing and it brings T down in exceptions only.
>>
how do i kill my libido? i don't get boners randomly but i do when im horny and thats pretty much all the time.. i only take e atm and have female range t
>>
>>12698274
Once you stop doing lewd things to yourself for a while, ~2-3 weeks, libido tends to plummet. Anecdotal evidence, but hope it helps anyways <3
>>
>>12698290
ok ty
>>
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104 KB
104 KB JPG
To any femanon here: I'm interested in trying patches instead of pills. Is Climara good quality? Estradot looks like crap desu, not sure about the others.
>>
>>12698512
w-what's wrong with estradot?
>>
>>12698214
call me when they have good enough lupron spray

or probably lupron depot goes down in price

or you know, get on the monotherapy meme.
>>
Attempt 1: stuck a vein
Attempt 2: found a muscle but forgot to z track
Attempt 3: success

Why am I retarded
>>
>>12698209
Anon two years is a lot, it may already be too late. Do you ever see an Endo or therapist?
>>
>>12698512
there is nothing wrong with estradot, i used them for a year with a solid 250pg/ml level of E
>>
>>12694027
>>grandfather gave up his cancer treatment so I could have this and now he's dead and my only living parent won't talk to me anymore after I brought this up to them
jesus christ
>>
Will my alcohol hobby(not problem or addiction) affect hrt?
>>
>>12698846
"solid"
>>
>>12698268
It's suprefact, it's made in canada by sanofi-avertis.
>>
>>12698839
I have an endo but she's worthless so I'm thinking I'll stop seeing her. She said there's a chance I'll make some sperm if I stop HRT for a few weeks, but of course, 2 years is a lot and I'm not expecting anything.
>>
>>12676424
A few questions about hrt without breast growth:
is raloxifene actually E or does it just act like it and if it isn't really E, will it stave off the negative effects of bica monotherapy that are usually remedied with real E?
Could I use a small dosage of topical E along with ralox + bica and still avoid breast growth?
If I used a small amount of E would I still risk getting mpb and what type of drug is Finnasteride?
Might it be better to apply a small dose of topical T to my breasts and a larger amount of E to my scrotum along with an AA in order to get feminine features without breast growth?
>>
>>12690886
what would even happen if you inject sterilized dust into your body?
>>
>>12693780
that just means you injected more shallowly or you ate more calories or drank some alcohol that week so your body is metabolizing the bump more slowly
>>
>>12698268
you ordered the russian buserelin from the link in the first reply?
>>
What's this argument about high estrogen vs low estrogen being better?
>>
>>12698274
anti-depressants is the real answer
>>
>>12699675
250 is good for stable levels, patches don't spike like injections if you apply new ones on schedule
>>
>>12698825
Attempt 1: Fainted ten seconds after taking needle out, forgot to z-track
Attempt 2: Finally found muscle after drawing blood into the syringe a bunch of times
Attempt 3: Squeezed too hard on the ampoule while trying to open it and a mixture of glass and oil went into my hand
>>
>>12700353
just experiment and find the levels that work best for you
>>
>>12701234
I don't have the money to experiment.
>>
Is 25mg cypro too little? I guess I'm just kinda weird about it but I feel like nothing's happening. Should I do 50 for now or stick to 25?
>>
>>12700353
In theory high levels could induce receptors down-regulations. Low levels not enough activation.
>>
>>12701591
So... what does that actually mean in practicing treatment?
>>
Just started taking cypro and estrofem yesterday any advice? Also boymode advice on what to wear so mom doesn't kick me out?
>>
>>12702064
>
Feel your body.
>>
>>12676424
anyone from israel here?
>>
>>12676830
Change your diet and don't pick low carb
>>
it says on the lena website to have inbuilt needles, do i actually need to have an inbuilt needle? i don't see why i would but i wanna check
>>
>>12703619
It's to minimize trapped medicine in the syringe that will be discarded/wasted. They are cheap anyway.



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