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>Help, advice, guidance on medications and dosages
>HRT related medical experiences and research
>Availability and pricing of medications
>Rational and scientific discussion

Please take the survey and help us determine the best medications, dosages, and treatment regime to get the results we want.
See the first post for a pharmacy list.

▶ Survey: https://1drv.ms/xs/s!AudRJceTA5C9c2G5lCV2Avq0kQ0
▶ Raw survey data: https://1drv.ms/x/s!AudRJceTA5C9cyIWo6_X14AvHyM
▶ HRTGen Data Analysis: https://1drv.ms/f/s!AudRJceTA5C9gRLLWnbpdzlIxe4r
▶ HRT Anime Girl Info Sheets: https://1drv.ms/f/s!AudRJceTA5C9gQnyM7wxZcBGWRzW
▶ Pill Identification: https://www.drugs.com/imprints.php
▶ DrugBank Database: https://www.drugbank.ca/
▶ Basic HRT info: https://apps.carleton.edu/campus/gsc/assets/hormones_MTF.pdf
▶ Hormone target ranges: http://www.hemingways.org/GIDinfo/hrt_ref.htm
▶ Endocrine Society guidelines: https://academic.oup.com/jcem/article/102/11/3869/4157558
▶ Callen-Lorde Guidelines (with flutamide) http://callen-lorde.org/graphics/2018/05/Callen-Lorde-TGNC-Hormone-Therapy-Protocols-2018.pdf
▶ TransDIY: https://www.reddit.com/r/transDIY
▶ Breast development info: https://genderanalysis.net/resources/studies-on-trans-womens-breast-development/
▶ Blood testing (US Only): https://www.privatemdlabs.com/
▶ Blood testing (UK, Ireland): https://www.medichecks.com/
▶ Blood testing (Canada Only): https://bloodtestscanada.com/
▶ Blood testing By Mail: https://www.letsgetchecked.com/ - DIY capillary blood samples get mailed in to the lab. Expensive.
▶ Lab test guide (with reference ranges): https://www.healthcare.uiowa.edu/path_handbook/index.html
▶ FtM HRT guide: http://www.ftmguide.org/ttypes.html
▶ /HRTGen/ Archives: https://1drv.ms/w/s!AudRJceTA5C9fiPMDzSLX7xF9MI
▶ More Archives: List at 8ch /tttt/ HRT Info Dump sticky
Previous thread: >>11477770
>>
The online pharmacy list:
inhousepharmacy.vu has been popular in the US.
eu-aibolit.com is a reliable site that ships to a lot of places. Good for EU anons. They list shipping rates for the UK, Canada, and US among others so I guess they ship there. http://eu-aibolit.com/content/15-usloviya-dostavki
shesalady.co.uk reportedly ships to Canada. You need to email the site operator to order. In the EU shipping times of two weeks have been reported. Email contact@shesalady.co.uk to order.
unitedpharmacies-uk.md seems to work for the UK.
There's also unitedpharmacies.md (US-centric) and unitedpharmacies.nl (Netherlands-centric)
alldaychemist.com is another.
https://inhome-health.com/ seems iffy so consider them a last resort. They reportedly ship to Canada.
http://fast-pharmacy.com/product/Evista.html has raloxifene and some other meds but is expensive.
>>
Pretty sure about my dysphoria but want to be 100% sure before taking estradiol so I'm gonna start with 25mg bica and then move up to 50mg. I know AA's aren't as feminizing as estrogen is, but what are other's who have done solo bica's experiences with feminizing changes? Read the chart in the OP link but was wondering about firsthand experience as well.
>>
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How to lower T

25mg cypro atm, I see people with testosterone levels below 10 with lower estrogen levels than me and idk how
>>
>>11505224
did you start at 50mg cpa?
>>
I'm scared that I'm just not a good responder to HRT. That doesn't make sense tho, we all have estrogen receptors, why wouldn't it work the same for everyone?


>>11504853
Was on sublingual Estrofem for a year, then oral pills for 2 months, then injections for a little more than a year now.
>>
>>11505224
that's literally a normal level for female T, it even says so in your pic
>>
>>11505232
No, state at 25mg. 4 months into hrt

>>11505457
As a mtf I should aim for lower than normal tho right?

It also says my LH/FSH levels are normal for female when it isn't too so.
>>
I'm just about finally coming to terms with myself but I'm so lost as to how to really go about all this. I'm 18 and live in the uk, should I just go for a blood test and see things from there? I don't really want to tell them much but I will if I really have to I guess
>>
>>11505716
rip didnt see ftm gen deleting and copy/pasting
>>
>>11505662
Get a referral from your GP to get on the waitlist for the gender clinic and then start diy.
>>
How long do you guys think boymode can last? Been at it like a year now and I'm not sure if people actually notice or not. I had some weird looks from family at christmas though.
>>
>>11505852
Idk, I'm gonna start HRT soon and I'm too awkward to ever come out as trans but my hope is that I can slowly fail boymode more and more until it's pretty much an open secret that I'm on HRT.
>>
How long can you last on Cypro alone? And what dose? I have 3 weeks of E left.
I think the CBSA seized my package since it didn’t arrived in a month.
I have to open a PO Box and order another package.
>CBSA stole months worth of hormones, best gatekeepers.
>>
>>11505852
Why would they look at you weird? Is your face that different?
>>
How soon after starting HRT should I get my first blood test(besides pre HRT baseline)? I’ve been on E for about 5 weeks, and on cypro since mid October.
>>
>>11506202
I have no idea, but probably.
At work I'm not sure if people know or if they just gossip about me being trans as an insult for how I look.
>>
I started HRT a month ago. I'm currently taking 2mg of Progynova and 50mg of cypro. My libido dropped to zero and I feel great about it, cos know i really know it not just some strange fetish. Now I want to be a woman even more. No big changes besides sore nipples from time to time. Should I lover cypro to 25 and raise estrogen to 4mg already, or just wait a little bit longer?
>>
>>11505988
If it’s only for a few months you should be fine. From what I understand a lack of sex hormone only becomes a real issue after about a year.
>>
>>11506249
3 months is standard. The doctor should recommend when they want to get you tested, but it's common to increase gaps between tests by 3 months until you get up to a year between tests.
>>
>>11506299
Would that be three months after starting E or starting cypro?
>>
>>11506285
If you've had no adverse reactions then go for it. Increasing after a month is perfectly acceptable.
Also are you taking the pills sublingually? If not, you should start doing that.
>>
>>11506342
Thanks. I was taking them orally with water as leaflet says. From now I will keep it under the tongue.
>>
>>11506409
Progy has a super thick enteric coating. Make sure you split them into halves or quarters with a pill cutter if you can otherwise that coating takes hours to dissolve.

Alternatively just chew the pill and swirl it around with your saliva for 5-10mins like it's mouthwash. That's what gave me the best results.
>>
What type of estrogen is in Estrofem? I know there's different types like estradiol valerate and such, but it just says "Oestradiol"
>>
>>11506432
Per the package, "oestradiol as hemihydrate"
>>
>>11506311
Up to you since hormone panel blood tests are just there to see how you're responding so dosages/drugs can be adjusted accordingly. If you've already had your liver and blood clot risks checked at your baseline appointment, then getting tested three months after you started E will be fine.
>>
what is the safest AA?
what is the cheapest AA?
>>
>>11506461
Gnrh agonists are safest.

Cypro is the cheapest once you've reduced to 12.5mg. It is a more expensive initial start. Spiro is the cheapest to start with by a small margin but you cannot decrease spiro dose over time like you can with cypro so long term pricing suggests cypro is cheapest.
>>
>>11506446
You had a blood clot test? Are you sure? I've never heard of clotting factor tests used in trans care. It's usually a rare test only given to hemophiliacs and it's super expensive pretty sure.
>>
>>11506512
Don't think there's a test for it, doctors usually just determine risk since it is possible (albeit pretty low occurrence) on estrogen
>>
Is 50mg cypro every two days the same as 25mg everyday?
>>
>>11506519
There are tests but you can't do them pre-hrt. DVT risk can be detected by a clotting factor test
I don't think it's something you can easily request though.
>>
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I'm 4 months in taking 50mg cypro and 4mg estrogen daily my legs have started to brake out in hives could this be related? blood test are 182 for E and 1.2 for T
>>
>>11505003
I am on 150mg spiro and it more or less nuked my t, which actually feels amazing .
I am thinking about starting progynova but I want to boymode for a while (it's dangerous to be transgender in my country)
Should I just take 1mg until I can leave or is starting on 2mg better not an issue?
>>
I've been on cypro for a year now. 12.5mg/day, my T counted 12ng/dl a month ago, my orgasm is 99% dry

However, lately, i've been feeling ultra horny, and my thing is going hard often. It's not the same horniness as i remember on full T, i just go crazy and dizzy now, but i'm still worried if that's a sign T went up. Could it be the case?

By comparison, at 25mg my T was 3ng/dl and i got told it was even too low, so i don't know if i should go back.
>>
anyone have positive experiences with progesterone?
>>
>>11506409
taking progynova sublinqually would be of no benefit as its not micronized. estrofem is generally used for sublingual, along with other micronized variants.
>>
>>11507550
Also curious

I'm on 25mg cypro and 4mg estro, thinking about adding a progestogen
>>
>>11505003
I've heard Black Cohosh supplements give effects similar to estrogen. Should I try them before I can gain access to HRT?
>>
>>11505003
I'm about to start DIYing HRT and and have already lost 30lbs and am about 25 pounds from my goal weight. Should I keep losing weight when I start HRT or should I maintain my current weight for a few months until HRT starts redistributing fat before I lose the last 25 pounds? I'm MTF if it matters
>>
>>11507869
Why do I see this "should i lose weight before HRT" question so much? Does nobody understand how fat distribution and turnover works?
>>
>>11507933
I honestly on't understand it, I've heard people saying that it's recommended to only eat one meal a day since intermittent fasting causes the body to redistribute fat faster
>>
>>11507590
this is objectively wrong
many anons have proven results from sublingual estradiol valerate, including prog
>>
Is 10mg/week injections a low dose? Someone here said I could even go down to 5mg, but someone today told me it was a low dose?
>>
>>11508386
that's a fucking huge dose
>>
If anyone here's taking oral progesterone atm, how much are you taking per day and what kind is it?
>>
>>11507590
i believe it is often micronized though
>>
>>11508418
Why did they prescribe such a high dose? Is it because they saw how much of a hon I was? ;_;
>>
>>11505058
I'm currently taking exclusively bica right now and have been since July. I started with 12.5mg (1/4 of the tablet) to 16.7mg (1/3). Maybe I just have naturally high estrogen, but I've actually started nipple development: budding around the nipples; v sensitive, stiff breast tissue just underneath the nipples. My nipples are now visible under my shirts and my chest has a bit of chunk to it. I doubt any of it is permanent, but I'd definitely start lower than half a tablet.
>>
>>11508548
nah, 5-10 mg / week injected is normal actually
but I think most people go with 5
>>
>>11508549
Oh and I feel like I needed to add, I take those doses every day just because it's easier to keep track of. Also, the reason I started at 1/4 was so that my body could acclimate - always gotta dip your big toe when starting medications (and taper off when stopping)
>>
>>11508549
when are you going to go full HRT
>>
is bica stronger than the other AAs?
and would anyone here trust Accord Pharmaceuticals Bica? they are a Chinese company
>>
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How long after upping your dose is it suitable to have a new blood test? In my case I went from 2mg to 4mg Divigel/Sandrena estrogen gel a month or so ago. My endo wants to have the test 3 months after I swapped dosage. Is this time really needed for the levels to stabilize or is like a month enough?

My levels at 2mg were 80pmol/l. And after 5 days of 4mg it was 210pmol/l. Though the second test was taken when I had eaten before and at like 11 am, so I'm not sure if its the estrogen that caused the higher level or if it was food. I also had 80pmol/l at up to 6mg swallowed oral progynova and 80pmol/l at up to 6mg estrofem sublingually. I have rheumatoid arthrithis and hypothyroidism. I feel like my body is incapable of absorbing the estrogen medications, I've tried everything except patches and injections. Speaking of injections...

Also bonus question, has anyone ordered from here http://lena.kiev.ua/EV/ and what is your opinion of it? Please don't make a comment saying its fake because the website design is lacking so is 4chan.
>>
how come spiro is the most popular drug, but so many people here say it's shit and not to take it??
>>
>>11509031
It's not the most popular drug, cypro is banned in the US so they just cant get it
>>
I'm hoping to reduce my cypro from 25mg (currently working well) to 12.5mg, are there any good signs for whether my T has gone too high? I can't currently get any tests.
>>
>>11508685
If I do, it'll probably be as soon as I can afford to get laser on my face, neck, and chest. Laser only works on dark hairs and taking E can lighten/thin them by a bit giving less of a result. I may not go full HRT, I always liked the look of bony, androgynous chests. I probably will, though.

>>11508900
Get tests every 3 months for a couple years then 5, then 7, I believe. You'll eventually only do them once a year or less.
>>
>>11505003
For injections how important is syringe size and needle ?
Like, I have bought neofollin from aibolit,
But before I did I didn't look at needle prices, and I'm not sure I can afford it...I have some halfway sketchy 10ml syringes, with a 21G 1.5" inch needles for it, from a company called romed holland. How risky would it be to drawn and inject with the same needle? how risky would it be to inject with a little air still in the syringe?
>>
>>11508835
bica is stronger then spiro, but cypro is hard to say
>>
>>11509031
spiro is very safe even if annoying
bica is only gaining popularity yet (the old guides still recommend flutamide and it's not healthy at all) and it's less safe
cypro is often considered not safe or is not certified in that country like it's in the usa
>>
>>11509897
If you smell like a boy T is probably high. I wouldn't do 12.5 mg without blood tests because it does not work for everybody.

>>11510577
I used to draw and inject with the same needle (also 21G 40mm) and never had a problem, I also used to buy syringe+needle at local pharmacies for ~50c each, it must be cheaper buying from online providers. Smaller syringes, like 2-2.5 ml, will be easier to handle but you can use any size.

There's no risk in injecting a bubble of air into muscle, some people even do it on purpose because it supposedly helps the medication to stay deep into the muscle.
>>
>>11510683
I'm not actually sure what I even smell like now. But I guess if it gets intense I'll know.
I'm positive I had low T before I started 25mg so I have a feeling I'll be okay. I need to reduce it so that my pills last (hopefully without fucking myself).
>>
>>11510683
>you smell like a boy T is probably high
I don't even know what my own smell is like, how the hell can I tell

I smell nothing from my body
>>
why is unitedpharmacies always out of stock? that shithole is the only place that will let me pay with btc
>>
>>11510956
cause I'm buying them all out
>>
Does anyone have any clue what are the long term effects of bica monotherapy?

I'm gonna go to the doc tomorrow because my heart/left arm area has been feeling weird as hell regarding circulation since yesterday and I'm afraid that like maybe I'm the ultimate unlucky bitterhon that's unable to even take estrogen without heart giving out so I'm curious like what are the potential alternatives. I really hope I'm overreacting but like the question might be of interest to like the femboy types anyhow.
>>
Anyone have any info on the lethality of hrt? If I took ~100 estradiol pills sublingually what would happen? Spiro?
>>
Someone stop me from ordering these pills.
>>
>>11510870
trannies can smell bad too, the difference is they don't notice it
don't listen to that anon

>>11510956
they're the most reliable pharmacy on the net
kill yourself
>>
>>11511429
Pills won’t make you a woman. Nothing will. You are only sterilizing yourself in pursuit of an impossible dream.
>>
>>11511434

thank you. I need some support
>>
>>11511449
You will always be male...
but with these pills you can be a cute male with boobs
>>
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>>11511452
>>
>>11511429
get injections instead

>>11511411
E2 - giant mood swings, vomiting, maybe some other shit
spiro - you'd pee yourself to death and then die from hyperkalemia or whatever
>>
>>11510683
>If you smell like a boy T is probably high
My T is nuked and E is 245pg/mL.

I don't remember what I smelled like when I had T, so I don't even know if I smell different now or not desu

--

What would the equivalent of 4mg a day oestradiol hemihydrate (taken bucally) be for patches? How about injections? Is it worth making the switch if I already get good results?
>>
Is there merit to fluctuation in my doses to mimic normal female puberty?

E.g. once a month going from 4mg to 6mg for a week and then back down? My levels are good as it is, i'm just curious.
>>
>>11511549
Not really, your body already fluxuates ur levels naturally once ur E is above a certain level.
>>
what blood test do i order from privatemd if im on bica and estradot patches?
>>
>>11511992
Female hormone test
>>
what length of microneedle do i need for hair growth? and what strength of minoxidil?
>>
>>11512314
>what length of microneedle do i need for hair growth?
1.5mm

>what strength of minoxidil?
3-5%, I use 5%
>>
How long to see results with minox/microneedling with nuked T and good E levels?
>>
>>11512389
For me it was about two months that it became noticeable, while needling once a week.
>>
>>11512320
When are you supposed to apply the minox? Right after needling?
>>
>>11511173
long term effects for me were realizing i’m an egg and going on a full e dose
>>
>>11512547
Twice daily except on the days you microneedle
>>
>>11505003
Is weight a factor when it comes to patches?
I'm currently 78kg and I barely get 100pg/ml E2 from 2 100ug patches.
I put them on my stomach/just below my ribcage. Should I try elsewhere? I used to put them on my thighs but it was worse there.
>>
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>>11513038
Damn that is unfortunately low for patches. When I used my patches it was on my upper arm between the shoulder and elbow. That spot gave me these levels on the same dose of 2 100ug patches
>>
what are tranny eyes? what does hrt do to your eyes?
>>
>>11513092
Makes your eyes look like a zombies because the estrogen rots your brain and makes you stupid like a zombie
>>
How long should 80 patches of Estradot 100 last?

Is it two patches per 7 days or more?
>>
>>11513103
thanks I needed a laugh

>>11513038
yea if you're overweight, your fat tissue can interfere with the absorption of E2 into the bloodstream
>>
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Is there any rational reason for an Endocrinologist to put someone on finasteride only as an anti-androgen? I've been on 12.5 mg cypro for two years and I've been experiencing severe side effects from it nearly from the beginning.

Estrogen is in the mid 200s on 4mg Estrace and my testosterone is in the 20s. Is there any possibility my body has just stopped producing as much testosterone and I'll be OK on this? I started HRT at 17. Really freaking out right now.
>>
>>11513061
There's enough room for 2 patches on each arm, did you use estradot? They recommend to leave each place patch-free for at least a week before putting a new one on. You need 3 sets of places to do that.

>>11513140
I am losing weight but I am worried about starting too much and hampering breast growth. I'm 6 months in and I almost have B cups, I think, though the pain has stopped recently.
>>
>>11513139
estradot lasts 3.5 days each and 1x 100 mcg/day patch = 2 mg sublingual E2 per day but as we can see here some people don't do well on patches and might need an excessive amount to get good levels
if you're doing 2 patches at a time you'll need 4 per week so you have a 20 week supply
>>
>>11513171
Yes estradot. After both arms I did my thighs then went back to arms.
>>
>>11513164
Why not go on fina? It has barely any side effects and DHT is ultimately what produces almost all of the negative effects from testosterone.

If you're not going to use any AAs you don't have much to lose by adding fina.
>>
>>11513203
I'm still on cypro right now actually, but just had an appointment and was prescribed finasteride instead. What should I expect? My concerns with cypro was the depression and low libido.
>>
>>11513223
Fina has no side effects. Even liver wise there is no known toxicity. If E alone is enough to suppress your T you'll feel way better on fina.
>>
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When am I Gonna get my skittles???
>>
With UnitedPharmacies US centric, does it matter which one I choose other than the price for Diane 35?
https://www.unitedpharmacies.md/Diane-Cyproterone-Acetate-Ethinyl-Estradiol.html
Does it only change the language but everything else is the same because I'm not seeing any difference.
>>
>>11513312
Which site is that?
>>
>>11513326
>https://inhome-health.com
>>
>>11513321
email them and ask directly, or just choose the country that you're in
also you should get real HRT meds not birth control
>>
>>11513421
I was planning on Diane 35 and estrofem. Should I do estrogen and cypro or Spiro?
>>
>>11513441
estrofem and cypro, it'll be called androcur or procur
>>
>>11513479
Okay, thanks. I thought I read that Diane would be good, but I probably should've gone with Cypro in the first place, thank you. I really don't want to mess this up
>>
I can't use my address for the billing address for unitedpharmacies because my mother opens all my mail. What should I do?
>>
>>11513583
sue her ass because that's a federal crime
>>
>>11513597
She doesn't have shit, so why would I do that?
>>
>>11513479
Or Siterone.
Procur has apparently been discontinued, according to IHP, and unitedpharmacies hasn't had it in stock for a while now (though the site says it'll be available).
>>
>>11513615
to put her jail without opening your package
>>
>>11513632
Dude she's my mum
>>
>>11513647
did you just misgender me shitlord
>>
>>11513659
REE
>>
daily reminder that estrofem is for hons
>>
>>11513756
You're wrong tho
>>
>>11513756
I don't even know what a hon is
>>
>>11513756
>teehee I'm taking a medicine with "fem" in the name, this will make me a cute anime girl uwu!
>>
>>11513808
Would you rather us take oestradiol instead?
>>
>>11513756
>Tried patches, great levels but bad skin reaction
>Tried gels, terrible levels
>Can't get injections
What else am I to take but sublingual estrofem? Its my only option besides oral pills
>>
>>11513837
take testosterone
>>
>>11513889
Nah
>>
How can I find more info on getting the right oral progesterone? It seems like it's barely ever mentioned anywhere.
>>
>>11507813
Unfortunately it's just a meme. Homeopathic stuff is always pseudoscience, which I found out for myself before I started on HRT.
>>
>>11513092
look at pictures of men and women and notice how men have peeled eyes; women have open, attentive-like eyes
>>
>>11513164
you should stay on an AA though or T will erode your work. have you considered DIYing bica?
>>
>>11513164
disregard what i said in >>11515456, turns out E is enough to suppress T once T levels are low
>>
Is 2.5g gel .06% daily enough? It’s supposed to be similar to 1mg/d oral and yield 60pg/ml.
>>
>wanted to start last month when i was 19 but couldnt because of the holidays and stuff
>turned 20 now and wanted start this month but cant because everything is out of stock and i have to wait until next month

looks like its the eternal waiting for me :(
>>
I know it's common to get dick leak on HRT, but should i be concerned at all if it only started after 2.5 years on HRT?
>>
>>11516201
your mileage may vary
gels and patches do fuckall for me
>>
I made a thread about it but no responses so I’ll ask here:

Is insomnia a common side effect of estradiol? Or am I just on extra levels of anxiety for whatever reason?
>>
>>11518743
nope, I stayed up late as fuck before starting HRT, but now I'm sleeping at normal times
>>
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So I had been self-medding 50 mg cypro and 2 mg e three weeks prior to getting my blood taken, and this was back in November. I finally got my results back. How are my results? Good? Bad?
>>
>>11519016
Meant 25 mg cypro. I just started my transition back in November. Did it really nuke my testosterone in those three weaks, or was I low T in the first place?
>>
>>11519038
did you have any symptoms of low T before starting?
>>
How do you girls get so low T concentrations? I have 40 ng/dl with 25 mg cypro, and it was similarly high when I was on 50 and high estradiol levels.
>>
>>11519362
that's female range T
>>
>>11519362
That's where I'm at anon, no worries that's within female range

>>11519016
Your estrogen is still super low and quite a ways from what you want it to be, but your testosterone is about as low as it'll go desu.

Like other anon said, did you have low T prior? My levels (see >>11505224) were also 25mg cypro and 2mg estro for the first 3 months, 4mg estro the last month. Looks like you're on the right path.
>>
>>11519328
I think so? Before HRT, when I tried hitting the gym I made like no gains. Also depressed and had/have feminine curvy hips.
>>11519362
I'm Asian.
>>
>>11519560
y-you lifted before HRT too? do a lot of trannies do this before transitioning?
>>
>>11519595
Er, well, I tried to yeah. Again, I literally made no gains and gave up after like 3 months. This was before I even knew transitioning was possible, so I thought lifting would make me happier for some reason. I'm 19 btw.
>>
I feel like my urine smells weird like some medication or chemicals in a cream I can't describe it since I switched to injections also I've been having erections a looooot everytime I get horny my whole body get so sensitive and I get boners!! This didn't happen on pills and AAs.

I'm not using AAs because my T was nuked just before starting injections it's been only almost 2 weeks on injections. And I was 1 year on pills
>>
I'm switching from reg to femboy hrt to better perma boymode. My ralox has arrived, but not bica. How would cypro interact with ralox, should I still do E at a lower dosage? 2mg estrofem from 4?
>>
>>11521963
>How would cypro interact with ralox
probably better than bica + ralox, bica in that scheme is suggested to keep fertility mostly

they have some interaction though, you might decrease your cypro dose

>The metabolism of Cyproterone acetate can be decreased when combined with Raloxifene

https://www.drugbank.ca/drugs/DB04839#interactions
>>
>>11521963
yikes, just stay on real HRT and don't shave if you want a perma boymode
>>
>>11522005
Would 1-2 mg estrofem, 12.5 cypro and 30/60 mg ralox work? I've seen some body building forums suggest 30 was enough because it raises T.
>>
>>11522056
i wouldn't take estrogen with ralox, also 60 mg of it is already a lowish dose, a rough equivalent of 2 mg of e
>>
>>11522103
How would they interact? What about T raised from ralox. I still have some time for hip growth would ralox still induce it?
>>
>>11522140
just take real HRT jesus
>>
>>11522140
If anything ralox will prevent hip growth. It's designed to have exceptionally high activity on the skeletal structure so it will fuse up whatever you have left quite quickly.
>>
>>11522250
I have to hide it from my family, would tamoxifen work? I would have to accept missing hip growth.
>>
>>11522646
Tamoxifen would do the same as ralox. They're both meant to prevent osteoporosis so their highest level of activity is on bones.
>>
>>11522646
tamoxifen has way worse side effects, it's better be avoided

>>11522654
>>11522250
what
they have estrogenic effect on the bones why would they fuse them
>>
>>11522646
>I have to hide it from my family. I would have to accept missing hip growth.
>permanently sacrificing your body for two people you'll only live with for a few more years max
>>
i strongly doubt the idea that ralox would cause "missing hip growth"
>>
>>11522691
Estrogen fuses bones.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098010/
There was a case where they used high dosages of estrogen to stop the growth of a child cause she was handicapped. Can't remember the name though.

Once everything is fused having high estrogenic activity on bones is desirable though. Possibly even better for skeletal changes (only like 3% of bone turnover is due to bone modeling past puberty, but high dose estrogen may increase that).
>>
>>11522855
>Epiphyseal Fusion and Cessation of Longitudinal Bone Growth
it is about the growth plates and *longitudal* bone growth not about hips getting wider... estrogen stops the growth of limbs etc but makes hips wider

>“Pubertal rise in estrogen concentrations mediates the widening of the pelvis and the high estrogen levels during the time of highest fertility maintain the width of the pelvis,” Ponce de León said. “The postmenopausal fall of estrogen concentration results in narrowing of the pelvis.”
https://www.huffingtonpost.com/entry/women-pelvis-shape-lifetime_us_571f9b6ae4b0f309baeeb23d
with animations and shit
>>
Okay, just got my levels tested. I am at 92.7pg/ml. I am taking 6mg of estradiol, 200mg spiro.

I started at 2mg e 50mg spiro, month later I was on 4mg e 100mg spiro, one more month I was on 6mg e 200mg spiro, after that month I had my first( and only) testosterone test and it was 9.8 ng/dl. My Dr wanted me to go on 8mg, but I felt sketched out but that, so one month later(had been on 6mg for 2 months now) I got my e tested and it was 98pg/ml. 3 Months later, I get it tested again and I was at 92 pg/ml. Should I up my dose to 8mg or stay at 6? My blood work was usually around 4ish in the afternoon, I take my meds split up at 7:30am and 7:30pm.
>>
>>11522969
so you hondosed yourself, even with your doc telling you to take more
yikes
>>
>>11522967
If you think it's a good idea to try then go for it. But estrogen therapy has been used to intentionally stunt growth so I wouldn't trust it.

If you're like 22-24+ years old then yeah you can safely nuke your body with E and you'll see nothing but benefits skeletal wise.
>>
>>11519850
The reason for this is because there are more androgens in the genitals, most AAs also block receptors, and in the case of spiro it lowers blood pressure which reduces erections, for cypro it raises prolactin which does the same thing.
>>
Has anyone used Estraval Depot from IHP? Or do you know if it's legit?
>>
What's the deal with alcohol reducing the effectiveness of cypro?
I know about the liver risk but does it really make cypro work less?
>>
>>11523025
nnot me
>>
>>11523407
I drink on cypro and my liver is fine.

T is in female range, E is over 240
>>
>>11523512
how often? I got really drunk (off only 3 beers or less though) about 4 nights in the past two weeks. That's the first time in a while though.
>>
when i'm figuring out bloodtests online, does it matter whether I do the hormone panel for men or women? Will it just spit back all the same hormones but with guidelines on whats good based on the gender you gave them? I'm early HRT and boymoding so if I can avoid somebody giving me weird looks for putting she, I'd like to, but not if it'll fuck up the results somehow.
>>
>>11505399
We all have receptors, but not necessarily the same amount. And they still have to activate the appropriate genes. Some people are just unlucky. But you should keep trying different things. Patches work better than injections for some people.
>>11505580
You don't necessarily need lower T than normal. You are in the 8-48 reference range barely. But you've only been at it four months. With FSH and LH so low and E so high I'd expect T to continue dropping.
>>11506623
Pretty much. The half life is long enough that you can get away with it.
>>11506789
You should be able to halve cypro right now. I haven't heard of anyone getting hives from these meds but urticaria is a possible side effect from cypro and even estradiol pills. Maybe you should change brands to see if that helps. Your T is so low you could maybe stop taking cypro for a week and see if that helps.
>>11506790
1 mg will probably give you slower progress. 2 mg is probably enough to give decent feminization.
>>11507476
As long as you're dry I doubt your T is up. You do not need T to be horny or even to get erections. You can always test again if you're worried.
>>11507813
Don't even bother. Pueraria mirifica would be better than that. But you should try to get the real thing.
>>11507869
Just keep losing down to your target weight.
In the long run - as in over several years - your fat distribution will end up the same in the end no matter what you do.
And when you're losing hrt will change the pattern of loss anyway.
>>11507955
>intermittent fasting causes the body to redistribute fat faster
Do you have a citation? I'm skeptical.
>>11508386
Whether it's low or high depends on what levels you get from it. It's not out of the ordinary as a dose but you need a blood test to know what's going on.
>>
>>11508422
For micronized progesterone 100-200 mg a day is usual. Whether to cycle is debatable though it might be a good idea. According to Brody's Human Pharmacology progesterone can decrease estrogen receptor concentrations so cycling could help avoid downregulation.
Makes me wonder if cypro might be causing that effect for some people.
>>11508835
Bica's the strongest receptor blocker. Cypro is strong at lowering T and also has direct androgen receptor blocking activity so it's pretty strong. But bica is preferred for prostate cancer treatment these days so it might be overall a bit stronger at reducing androgenic activity.
GnRH agonists are very strong at reducing T, but don't block receptors.
I'd be reluctant to trust Chinese pharmaceuticals unless they're manufactured under contract for a first-world pharma company and branded as coming from the non-Chinese company. A large amount of active pharmaceutical ingredients are manufactured in China under contract, but large pharmaceutical companies are at least able to do testing to maintain quality control.
>>11508900
A month should be enough for E2 levels to stabilize.
>>11509897
It's really tough without tests. Smell is one thing like the other anon said. Volume and consistency of cum, skin texture and oiliness, and body hair growth rates are things you could look at. I would not rely on anything to do with erections.
>>11510683
>some people even do it on purpose because it supposedly helps the medication to stay deep into the muscle.
Citation? That could be hon science. And subcutaneous works.
>>
I just started and my doses are 12,5 mg cypro and 2 mg progy. How long should I keep same dose?
For info my pre hrt levels are 11,58 nmol t and 82 pmol e
>>
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>>11524015
>Citation? That could be hon science. And subcutaneous works.
Probably nurse-science, I've only read about it on nursing journals and blogs. Of course, it wouldn't matter if estradiol leaks into subcutaneous tissue.
>>
>>11524047
OK, that looks like a legit thing. But like you said it's not really important with estradiol.
>>
What will hrt do if you already look androgynous? im 20 btw if that counts for anything
>>
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>>11511173
I don't think there's any particular lt effect other than the hormone effects. If you're getting elevated liver enzymes you could get progressive liver damage, but if you're normal with them then it shouldn't be a problem.
But it's a good idea to get things checked if you're worried.
>>11511411
There's no known LD50 for estradiol but large amounts can make you feel sick.
Spiro LD50 is > 1000 mg/kg in rats, mice, and rabbits. Hyperkalemia is possible but most likely you'll just get extremely sick and have the most miserable few days of your life.
Maybe you'll piss yourself to death!
>>11511449
Don't listen to them. Estradiol is a *female* hormone. It activates the female parts of your genome.
>>11511515
Equivalent would be 2 100 mcg patches, though for some people 1 patch would be closer. For injections 5-10 mg/week depending again on your physiology. I'd use 2x100 and 5/wk as the baseline.
>>11511549
>Is there merit to fluctuation in my doses to mimic normal female puberty?
No. There are diurnal variations but cycling doesn't normally start until ovulation begins.
To mimic puberty you'd be ramping up levels gradually over time. And the levels would be drastically lower than what you have.
>>11513092
There is a negative canthal tilt meme.
>>11513171
Instructions always say to put patches below the waist. I've never seen arms listed as an acceptable site, but references to the contrary are welcome.
>>11513349
Experiences with that site are mixed.
>>11513805
Manly looking unpassing mtf.
>>11513932
Cypro is a progestin.
Micronized bioidentical progesterone is what is normally taken otherwise.
>>11516201
That's pretty low. You'll likely need double that at least.
>>11516422
Do you mean urine leak? Maybe 2.5 years of atrophy caused it. You could practice starting and stopping urination to strengthen muscles.
>>11518743
In the estrofem leaflet it's listed as very rare - up to 1 in 10,000 people.
>>
>>11519038
It can nuke T in a month but you might have been low to start.
E2 is typical for 2 mg/day. You can go up to 4.
>>11519362
50 isn't necessarily better than 25 and in the study that got the recommended dose cut to 25, 50 mg was actually a bit worse for some reason.
Everyone is different though and some people end up lower. But 40 is a female level so it's OK.
>>11522967
From the animations it looks like at least some of the change is due to changes in the angles of pelvic bones. I'd have to read the journal article. I've never totally understood how hip growth was supposed to work. It looks like it's an active topic for study.
I'm not sure raloxifene would have the same effect as estradiol either.
>>11522969
Your E2 level is a bit low and your doc wants you to go to 8, so go to 8.
>>11523714
If you're talking about privatemdlabs just do the hormone panel for females.
>>11524021
I would have started at 25 mg cypro but 1-3 months is the time.
>>11524102
It should make you look more female. If you're andro you likely have a good starting point. But ymmv.
>>
>>11524226
>It can nuke T in a month but you might have been low to start.
>E2 is typical for 2 mg/day. You can go up to 4.
Is it okay to switch from cypro to spiro now that my t is low? I've been getting bad depression from cypro. I also live in the US if that's relevant.
>>
>>11524265
That's hard to say and I'm wary of a switch with E2 levels that low. Without knowing your baseline T it's hard to say how much rebound you might get.
I'd say you could cut cypro in half to 12.5 mg/day. And do go up to 4 mg/day of E. That might help with the cypro depression. If your T is still low and E levels good then maybe you could try going to spiro.
But if you really can't stand cypro any more you could try switching to spiro and hope for the best.
You could also try bica. 25 mg/day should work, or you might even be able to use 12.5 mg/day.
>>
>>11524015
>Smell is one thing like the other anon said. Volume and consistency of cum, skin texture and oiliness, and body hair growth rates are things you could look at
Alright, I'll keep that in mind. Seems like so far I'm all good.
>>
Why is turkish estrofem cheaper if its supposed to be the same thing?
>>
>>11524071
Different anon tho I know about someone who gets e injections sc and they use the airlock there.
>>
>>11524451
Trust issues
>>
>>11523618
Maybe once a week, a few drinks (5% peach ale) is enough to get ne drunk.

Did that for the past couple months, had my liver and hormone levels tested last week. All a-ok

>>11523714
Female hormone panel

>>11523964
That's good to hear. I want to kill T, its evil lol
>>
>>11524958
So is there really something wrong with it?
>>
just made my order looks like this is going to be the longest two weeks of my life
>>
>>11524451
isn't it a silly question? because it's made in turkey where the cost of labor is cheap, possibly from the raw stuff made in china or india where the cost of labor is cheap too
>>
so where do you get estradot patches in EU?

not gonna use shesalady, no fucking thanks and eu aibolit shows the price as 0?
>>
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Does anyone know if this is legit? http://lena.kiev.ua/EV/
>>
>>11524015
>Makes me wonder if cypro might be causing that effect for some people.
[CITATION NEEDED]
but you're right I might have to try taking a huge amount of E2 while skipping cypro for a week or two to see what happens
>>
>>11525429
that initial wait is horrible
stay strong anon
>>
ive been on hrt for a bit over 3 weeks now, ive gotten noticably softer skin and my face seems a bit different but i cant put my finger on it, ive also noticed that i smell different. its like i smell sweeter or something. and my nipples are really puffy and sensitive.
But now all my guy friends are really handsy all the sudden, its like they cant keep their hands off me. I havent told them im on hrt but is it possible that they somehow feel or sense that im more "femme" or something?
>>
>2 months HRT
>no tits just tiny breast buds
some of us were just not meant to be trans I guess
>>
>>11525975
where do they touch you
>>
I just got bloodtested and my trough E is at 117.6 pg/mL after 3 months of 4mg sublingual estradiol.
I have experienced a ton of hip growth. Admittedly I am just using a 6 inch ruler and a piece of string so it may not be accurate, but like 3-4 inches were gained.
I plan to start EV injections at 4mg, but this thread is scaring me about my hip growth. Would starting injections now cause too much estrogenic activity and stop my hip growth?

Another interesting note, I have been taking 12.5mg cypro every other day. I got tested on the nondosed day after 24 hours of no cypro. My T was at 28 ng/dL
>>
>>11526061
ive always been kind of socially akward when it comes to touching people so my friends havent really touched me much before. but now they keep wanting to hug me and touch my face, one keeps trying to grab my boobs and another keeps rubbing my thighs. it makes me feel weird, like horniness but it comes from inside my lower stomach and thighs, not my penis. especially when someone touches my nipples or inside of my thighs.
>>
>>11526089
wow that's pretty hot, but also kinda rapey
do they touch each other like that too?
>>
>>11526123
they only do it to one of my other friends, but they started doing it to me when i was a little over one week into hrt. im sort of okay with it but my friend grabbed my nipple really hard when we were at the store and it almost made me fall to the ground because i squeezed my thighs together, it felt so good but hurt alot at the same time.
>>
>>11526156
I'll never forget when I was still boymoding and made a bad joke, and my best friend punched me in my lil A cup boob and I almost cried.

He didn't know I was transitioning. Probably thought it was weird I flinched if he made any sudden movements near me the rest of the night lmao
>>
>>11526222
yeah, i feel you.
a couple guys at work keep touching and pinching me aswell, one of them is the only person ive told im on hrt but he was like that before i started aswell. he is considering starting hrt aswell but he is hesitant.
>>
How long should I wait to take a blood test to test if my injections are legit? are 24hrs enough?
>>
I'm gonna suck it up and order HRT, it's fine to ship it to a dorm right?
>>
>>11526712
yea but for valerate and benzoate it looks like the peak occurs 36-48 hours after injecting
>>
>>11526808
Thanks, will try at 36 then
>>
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>>11525767
I got it from here, pic related. Where they got this from I don't know.
This might not apply equally to every tissue. I'm sure it's true for endometrial tissue, the main target of progesterone, but whether breast tissue works the same way idk.
With cypro I haven't seen anything published that suggests a problem and most people seem to have no problems with breast growth and feminization with it. But there are enough anecdotal reports of problems to make me wonder if something more is going on.
We're not even close to mimicking the hormonal environment of puberty, and in those who already went through male puberty there doesn't seem to be a benefit to doing so. But it's possible that some of the things that are done differently from puberty are counterproductive. Early exposure to high progestin levels might be one of them. But this is speculation and it seems to be a problem only for a minority.
>>
hey what are the risks of boozing on estrogen
>>
>>11527092
none because you're going to do it anyway
>>
>>11525975
You probably smell different.
You might have some skin changes already too.
>>11526067
You wouldn't get so much bone growth so quickly. It has to be soft tissue changes.
Since you're doing well on a low cypro dose might as well stick with that.
If you're going to do 4 mg/wk of injections that's a somewhat low dose so I wouldn't worry. Though I could say if you are happy with your progress right now you don't need to change. If you're getting good changes at a decent pace you probably won't be able to speed things up any more. It's often best to stick with what's working.
>>11526745
It should be. They shouldn't be scrutinizing your mail.
>>11527092
It's mainly an issue with cypro and bica because they can affect the liver. It's also an issue with estrogens like conjugated estrogens and especially ethinyl estradiol that are harder on the liver. Swallowed bioidentical estradiol there could be a little but not a lot of concern.
Lots of drinking isn't good for liver health and function though and that could affect all kinds of things.
>>
I think I psychologically transitioned way faster than my body is transitioning, and now I'm dysphoric as fuck
this sucks so bad
>>
>>11525975
What have you been taking? Seems like nice changes for only 3 weeks.
>>
>>11524451
because the pharma industry’s material cost is pennies and everything is arbitrarily priced according to how much they can get away with in each country
>>
>>11527147
trutrans alert
>>
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Who delivers to US faster ADC or United? Paying thru btc
>>
>>11527457
I could've sworn you're a self-described chaser, why are you ordering HRT?
>>
>>11527496
Its for my """"roommate"""" Mom, why are you all up in my mix?
>>
>>11527457
i dont think anyone even orders from adc it looks really jank, just go with united
>>
>>11527548
I can't tell if you mean you're getting it for yourself or you're force feminizing a femboy
Either way, you're doing god's work
>>
>>11505003
Best site to order with paypal? I'm on spiro in California
>>
I’ve been DIYing 100mcg E patch + 25mg bica/day for 2 months. Any suggested changes? OP pic says E should be increased to 4mg which would be equivalent to 2x100mcg patches. Is that right?
>>
>>11527649
Depending on your blood results, you might want to look into upping the patches. I've seen quite a few people run two 100mcg patches at once
>>
>>11527667
Thanks. Should I keep bica the same?
>>
>>11527584
do any of them even use paypal? i thought paypal was just for scammers
>>
>>11527711
paypal is for people who want to be scammed; by paypal
protip: don't leave your money in a paypal account. they will block you from accessing it ie. steal it.
>>
>>11527147
I’m dysphoric about the fact that I can’t psychologically transition :’)

Is ridding the old self even possible for people who spent their puberty as a cis? Unless you were gay (“true trans”) seems like transitioning beyond 16 or so is a futile effort.
>>
>>11527849
I've heard of it but you have to basically start a new life. New town, new name, no connection to the old self at all.
>>
>>11527849
I mean you're going to be the same girl you were before transitioning, the main difference is what you identify as.
>>
>>11527710
Probably though you should test your T level. If T is still way up in the male range you should consider going to 50 mg.
>>
>>11527849
Unless you were a trans kid and went on puberty blockers and then went through middle and high school as a teenage girl, it's pretty hard. But transition is always at least the best possible scenario.
>>
>>11528068
This is the scariest thing for me to come to terms with literally right now.
>>
>>11528758
Every branch of realistic scenarios is a no-go for me. At this point I’m just taking HRT purely as an anti-depressant.
>>
>>11528800
i'm going to end up as a homeless hon tranny and sell my body for my next fix of tranny pills. Either that or suicide I guess.
>>
>>11529037
Canada by any chance? If you’re serious I’d help you out.
>>
>>11529061
*weren’t exaggerating the situation is what I meant, just to be clear.
>>
>>11529061
>>11529073
Yea I'm mostly exaggerating but I'm just feeling like shit recently. I'm in the US
>>
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>>11529061
>t. pimpdaddy honshuffler
>>
>>11529154
Kek, but no. I would have given some some of my hormoans if she lived near. Had a wrong idea about how E patches work and I bought like a years supply accidentally
>>
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>>11529167
"It puts the E patches on the skin"
>>
how long until replacement for patches? Optimal placement?
>>
>>11529208
I don’t understand anon
>>
>>11529229
Depends but usually it’s 4-5 days. For me 4 is optimal; longer than that my skin itches.

And upper thighs, front side, if that makes sense. I’m not good with body part names.
>>
how bad is it to microneedle your temples
>>
why the fuck are my estradiol levels so fucking low. 37 pg/mL. i feel like screaming. what can i do?! i'm on 6mg of estradiol tablets daily, but maybe i miss some dosages. i don't know. it's hard to keep track when you're fucking depressed as shit. at least my t levels are fine.
>>
>>11529269
Not bad at all.
Use the stamp, though, not the roller or you'll bleed a lot.
>>
>>11530062
for context, i've been on hrt for over a year now, and we can't fucking get it where it needs to be. i'm so irked right now
>>
>>11530062
>>11530077
so a full year on AA alone basically? how have you not killed yourself. also were you swallowing the pills immediately or were you doing sublingual?
get on injections ASAP
>>
>>11530146
sublingual...
I don't know if I can get on injections but I'll fucking try
>>
>>11530146
also, the last two times i got my e measured it wasn't TOO bad, it was around ~70, but it dropped since then, so it's not like i haven't been getting ANY e, just not enough at all... or maybe it doesn't work that way and i reall yhaven't been getting anything worthwhile out of my meds all year ;_;
>>
>>11529269
It isn't bad. I use a dermaroller 1.5mm once a week on my temples with minox twice daily for regrowth.

>>11530062
>>11530262
Try taking it bucally, much more effective. Takes up to an hour or two to fully dissolve, ensures none of it is wasted.
>>
>>11530282
Well to be fair, E2 levels with sublingual administration spike very high for a short period of time so if you blood test right before your next dose your E2 will look really really low but on average the levels are probably decent. What is most important is your results. Has anything changed for you over the year? But either way injections would be a nice upgrade if you can get them.
>>
>>11530313
yes i get called by female pronouns in public now and my boobs are slowly growing, it's just not as fast or intense as i'd like
>>
>>11530322
wow, nice
>>
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>quit HRT for 1 month mostly because thinking of possibly sperm banking
>immediately lose 30~40% of the hair on my head despite being on finasteride
>restart HRT

I can only hope the follicles weren't permanently damaged in that time.
>>
Redpill me on estrogen monotherapy. I bought a bunch of injectable estradiol valerate, since it's basically the only option I have.
>>
>>11530369
this is what u get for being falsetrans
>>
>>11530369
yea i mean sperm banking? gross

>>11530454
it's god tier HRT. cheap, low side effects, low health risk, simple, great T suppression, and great E2 levels
>>
>>11530454
where did you find injectable?
>>
>>11530493
Sweet. I'll just get my levels measured and adjust from there.
>>11530565
Lena.kiev.ua
I got 18 months worth of HRT for 170$, but the downside is it might kill me since she fills and sterilizes it herself, and I don't think she's formally trained in it.
Still a win-win in my book, though.
>>
>>11530653
so everyone is buying from that site now or what
people keep bringing it up
>>
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>>11505003
I found this on eu-aibolit.com

http://eu-aibolit.com/onkologiya/23642-bikalutamid-kanon-bicalutamide-canon-bicalutamide-tabletki-50-mg-30-sht.html?search_query=bicalutamide&results=11

it's literally 0 euros aside from shipping, this isn't a scam right? Is there anywhere else I can get bicalutamide in Canada?
>>
>>11530653
Strange website. Do they ship injections to the US?
>>
Femboy not in hormones here, i heard if you go in nofap long enought your testosterone drops and ive been in a 4 month nofap, but i really want to masturbate, would anal stimulation make me lose my progress?
>>
>>11530653
How long have you taken it and do you feel well?
>>
>>11531207
You've been memed, take bicalutamide if you don't want T
>>
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>tfw i actually got my doctor to prescribe me cypro
no more shady hrt buys for a while senpai
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>>11531207
>i heard if you go in nofap long enought your testosterone drops
you heard wrong
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>>11531365
where do you live
>>
Should I be taking Bica in the morning right after sublingual estrofem?
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>>11531022
Stuff that isn't in stock anymore is listed as 0€
>>
do locking syringes waste less medicine than slip types?
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>>11527162
50mg cypro and 2mg estrofem every day for 22 days. Im also "only" 20 years old.
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>>11531870
half life is long enough it shouldn't really matter, take it when it's convenient

>>11527572
oh it's guaranteed to be some creepy shit with him, like not helping someone but 'helping' someone
>>
>>11532196
Pfft I started at 20 and i'm already presenting (4 months hrt). Have faith, not starting at 14 doesn't mean you wont pass.
>>
so apparently they need to call me to verify my echeck, how long do i have to wait until they call me and what do they ask?
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uh does former steroid usage (testosterone and tren) have any effect on HRT usage? will it make it less effective or something? just wondering for a friend.
>>
>>11532693
>fellow /fit/ repressor
I never went on roids or anything but I can relate to your pain
>>
>>11533007
>>11532693
Ditto, was a bodybuilder in high school while repressing. It just made me more depressed and led to me finally breaking lol
>>
Is it okay to combine herbal HRT with actual HRT or does that somehow reduce effectiveness? I'm talking like natural AAs and phytoestrogens.
>>
>>11533313
It will do no good
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>>11532693
nah, see >>11495614
lots of weightlifters there turning into cute girls
if anything it will help because exogenous T is supposed to damage your natural T production or something isn't it?
>>
>>11533442
if you don't run Post Cycle Therapy, yeah
which I haven't
which is why I'm on /lgbt/ asking about hormones
fml
>>
>>11531173
Yeah.
>>11531319
I haven't; just got mine this week and am not sure how to dose it.
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>>11531833
germany
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>>11534624
has anyone in the US actually received a shipment from there?
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>>11531876
Thank you very much!

>>11505003
Is it the estrogen or the anti-androgen which kills your dick on HRT?
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>>11534793
Yes, I have.
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>>11536080
how much did you order at once?
will customs confiscate the order if you order too much?
did the injections give you good levels?
>>
>>11536203
Two vials
I wouldn't know. Two will last for 18 months, no need to order bulk
N/A, haven't measured yet, I only got them this week. People say it's effective, though.
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>>11536288
Tempting then. How much was it?
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>>11536288
how do you store the vials, especially after opening? refrigerate?
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>>11536022
both. spiro and bica will only get you 1/4 way there. E alone can in a high dose.
>>
>>11532693
>>11533312
>>11533007
can i ask a question, i don't mean it to be rude or accusatory, just how? i understand there's probably not a good answer
i tried a few times and it felt good to get my cardiovascular system back in shape and trim up a bit but every time i started seeing masculinization i just disintegrated and started starving myself or had a depressive collapse. not trans tho

>>11533470
unless you took something that permanently adversely affects estrogen receptors/hpg axis or did organ damage i don't think will have any effect once it's out of your system
and if it's something that only hurts test in the long run i don't think it will matter

>>11536022
both kill your testicles, e2 in particular is antigonadotropic iirc
once you no longer get random erections not using your dick is what kills it
you should try to get an erection and maintain it for a bit daily or do nothing if that's what you want
>>
>>11536780
it's called repression anon, be grateful you never had to suffer from that
>>
>>11536829
Nevermind then
Not looking to derail into suffering Olympics with some agp lifter
>>
>>11525764
>>11530653
That seems so sketchy to order home-brewed injectable estradiol valerate from there.
>>
>>11505058
i started with 25 for two months then felt i wanted more so moved up to 50. it's not clear how many changes were dose related vs time related. i ended up with mild gyno, skin changes, and a mild E-like mental effect. i went on full E after that
>>
>>11537952
i believe somebody from here ordered it and reported the blood tests were ok
>>
>>11505058
i take 50 mg/day for 10th month already, works fine, i feel my face somewhat changed and my smell probably too, breasts got puffy but that's all, which is fine because i don't want them anyway, did a few blood tests, alt/ast was ok, t even decreased slightly, e slightly increased, but well those don't say much in bica; kept my erections and most of libido

taking 25 mg is likely not enough, less than 25 is a waste of money
>>
I've been on cypro for almost 2 years and I run out tomorrow. I also ran out of E and I have no money for more. I was on 12.5mg for the last year and a half probably and my T levels measured at 22mcg/l last April. How likely do you think it is that my T levels will rise significantly if I don't get back on cypro within a couple months?

I do have some old spiro that I could take in the meanwhile but it isn't much.
>>
>>11538420
22 ng/dL rather
>>
Ok so since upping my estrogen dosage my sex drive has gone up like a lot. Is this a result from finally having good E levels, or should I be worried about my T levels or?
>>
>>11536780
>can i ask a question, i don't mean it to be rude or accusatory, just how?
It's similar to how, prior to coming out and while still figuring themselves out, some gays will continue to date girls to try and find the problem.

In my case, I thought my brain was just fucked up and if I "manned up" and got a better girl maybe things would work and how I felt would go away. Nothing as a man satisfied me, even sex just felt...wrong. I was never attracted to women but dating them made me feel "normal".

Eventually I realized bodybuilding was making me feel worse. I accepted I'm not fucked up im just trans, and that it's lazy that i'm trans and should stop forcing myself to ignore it out of fear of social repercussions, so I transitioned.

I've never been happier in my life than I am now living with my boyfriend and being myself.


TL;DR repression is a hell of a drug
>>
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Went to planned parenthood to get informed consent stuff a month ago. Before this I had been on 4mg Estradiol sublingual and 25mg cypro for six months.
They put me on 100 mg spiro (of course) and 10mg injections of estradiol twice a week. Seemed kinda messed to me but I was just happy to go legit so I didn't question it.
Went to a different one yesterday for reasons and they basically said the last one really did give me a messed amount, and now I'm on injections twice a month and still 100mg of spiro.
What the heck do I do, should I just reveal my power level next time I go and recommend a plan of action?
Kinda' sick of being messed with like this.
>>
>>11539698
Im on 25mg cypro 4mg sublingual end my levels are perfect

Honestly im probably going to go legit because I have to if I want to be accepted for surgeries in the future, but since I'll be prescribed spiro I'm thinking maybe I should just stay on the cypro and only use the fairi'm they give me? Like why fuck up my good levels for cautious doctors... right?
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>>11537938
What are you even talking about? Why do you seem so defensive and upset? You just said you weren't trying to be rude or accusatory and yet here you are attacking someone for stating how someone can be a lifter before starting HRT. It's not a competition to see who suffers more. We can say you suffered more if it makes you feel better, but that doesn't mean that other people didn't suffer at all. See >>11539565 for a thorough explanation. Again, there's no need to be aggressive.
>>
>>11539698
I'd be glad I'm on injections. What has your blood been coming out with? First 10mg twice a week was definitely excessive, but now its like they have you on too little at only twice a month.
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>>11537952
no more sketchy than buying bulk raws from purple panda, and then having to prepare everything yourself anyway
plus she's an AGP tranny and she knows what's up
>>
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>>11539744

I have no idea, the never showed me my results. All I know is that the first planned parenthood was trying to gate me because my the results showed my kidneys were functioning a bit too well I guess.

>>11539731

Honestly I have less ups and downs on the injections which I'm glad for but the spiro really does make you piss a ton. It's awful. I just don't know if I can order Cypro in the city I live in since I just moved, it got through really easy in the small town I used to live in.
>>
>>11539784
By the way do they do the injections or is that on you? You can also get blood tests independently if you want to check your blood, I woulnd't trust docs that don't tell me my levels.
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>>11539698
God damn you should have stashed all those extra injections or sold them or something
>>
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>>11539799

I do the injections myself. Luckily my BF helps me out with them though. And aren't those tests like super expensive?

>>11539808

They only gave me enough for a single month.
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>>11538420
rip your progress
>>
>>11539816
No the tests are like $55 from the OP privatemd link, very affordable and easy. Also damn I'm jealous that they let you do your own injections. You make me want to go official.
>>
>>11539565
>and that it's lazy
And that its okay*

Stupid autocorrect
>>
>>11539837

Huh, that might actually be doable. Thanks! Sorry I wasn't smart enough to thoroughly go through the op.
>>
I'm 10 months in and my breasts stopped growing at month 6, September. They are honestly disappointing, look like mild gyno and they don't hurt at all. Is this it or are they taking a break from growing?

163 pg/mL on patches (150 µg day) I will try to get a higher dose prescribed. Also, I'm lactating but I don't know if that interferes with breast development.
>>
>>11539816
>They only gave me enough for a single month.
10mg twice a week is enough for like 3-4 months if you split it up into normal dosages.
>>
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I'm in Ireland and shesalady is out of cpa and I'm running out.
Anywhere else I can buy it that ships here?
Also considering buying gel and wondering what the equivalent of gel would be to 4mg sl
>>
>>11539878
Some people have reported success by cycling their levels. Basically you can do multiple days in a row with low E (or none at all) then resume a high dosage.
The idea being to reset receptor concentrations and mimic the breast growth post-menopausal women experience when they go on HRT.
>>
>>11539885

Suppose so.

Too bad I was a "good girl" and took all of it already.
>>
someone please what is the best starting dose and how do i get my doctor to listen to me
>>
>>11539914
Silly girl, I'm stocking cypro because my endo insists on prescribing 50 mg.
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>>11539914
Tell them to up your injection dose again then sell me the extra vials okay thank you
>>
>>11539959

Roger that Senpai. Will report back in a month.
>>
>>11539878
Are you on cypro or spiro? cypro can help avoid gross gyno manboobs.
>>
>>11540029
how so
>>
My T is relatively low to begin with (my doctor is concerned that my T is too low despite not being on HRT), knowing this should I go Bica or Cypro?

Cypro seems likely overkill but is cheaper than Bica in the long run. Money isn't really a problem.
>>
>>11540052
it gives you gross dense conetits instead
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>>11540052
there was a bit on the wikipedia page about cypro being a progesterone promoter and good for promoting more natural looking breasts but the article has since been rewritten and i didn't save the source
>>
>>11540055
12.5mg of cypro is cheap and all you will ever need
>>
>>11538420
I'd definitely expect your T to go up.
You might as well take the spiro. It might help some.
>>11538733
High enough E levels can help sex drive. There was a study in ciswomen - menopausal I believe - that raising E2 levels to the periovulatory range helped sex drive. I can't remember the exact levels they were reaching but I'd expect it to be over 200 pg/mL. I wouldn't normally worry about higher T. If you are generating more and thicker cum then maybe you should worry.
>>11539698
10 mg twice a week is pretty high, especially to start with. On the other hand with estradiol valerate twice a month like at the new place is going to give you very uneven levels.
5-10 mg a week is a typical dose. Some people might need more but you'd want to test first. Definitely talk things over with whoever you go to next.
>>11539731
You could stay on cypro. Although spiro works better when T is low and since you already have low T it might be enough to keep it there.
>>11539784
You should ask for your test results. They are supposed to give you them if you request them.
>>
>>11540029
25 mg of cypro. They're a bit coney but I've seen worse. I was quite happy with how they were developing during summer but suddenly they stopped growing. I miss growing them and seeing progress every month desu.

https://unsee
.cc/6d451fcc/
>>
>>11539896
You could try eu-aibolit
Rough rule of thumb for gel would be the same number of mg of estradiol as you're taking sl. Then you have to calculate how many grams you need based on the percentage. So it would be 4 g of 0.1% gel and 6 2/3 grams of 0.06% gel. You might need more or less depending on how your body responds. I'd normally expect to need more. Like going by the OP graphic you'd need 7.5 grams of 0.06% gel.
>>11540146
Breast growth can happen in fits and starts but I've seen a lot of anecdotal reports of breast growth stopping on cypro.
I don't totally understand how things work with prolactin. Prolactin is supposed to help breasts grow some by developing glands, but that is mostly temporary because it prepares the breasts for lactation. It's possible that once you actually start lactating that the growth stops. This is speculation and I don't actually know. Anecdotally it seems like there are issues with cypro, high prolactin, and progress. Women wouldn't normally be lactating before reaching Tanner 5 and you're a long way from that.
There's also the issue in the pic here>>11527069
of progesterone downregulating estrogen receptors. Cypro is a progestin, though it isn't actually progesterone, so it might have that effect - ymmv of course.
>>
>>11540055
With low T you have a good chance of being able to go without an AA eventually. 25 mg/day bica would probably be enough to start. And if T gets well down into the female range because of estradiol you could go even lower or even stop taking it altogether.
Like the other anon said 12.5 mg of cypro would probably be enough as well.
>>11539921
It depends. Are you in the US? Do you want to get injections? Are you on a tight budget? Do you know your testosterone levels? There isn't a one size fits all recommendation.
>>
>>11540246
So strange how cypro has looped around over time.
>Get on cypro, its better for your growth than spiro since its a progestin!
>Years pass
>Cypro is starting to see evidence that it might actually be worse
>Spiro or other methods suddenly looking more positive
>>
New Thread:
>>11540806
>>11540806
>>11540806
>>
>>11540794
No, I'd still say cypro is better.
There was an NHS study with weak evidence of spiro users - if memory serves - being more likely to get boob jobs than those on other AAs.
Cypro only seems to be an issue with a minority of users. It might have something to do with prolactin.
The progestin issue is complicated and I don't think everything has been totally worked out. And cypro as a progestin doesn't necessarily work the same as progesterone, especially since progesterone can convert to other steroids.
And different tissues can respond differently.
There's some logic to holding off on progestins until you hit Tanner 4 because that would be most similar to how puberty works. It's often advised to wait 6 months to a year before starting progesterone anyway. A year would probably be better. The idea is to help finish development.
And it's probably a good idea to cycle off progestins for 7-14 days a month because constant high levels of progesterone aren't normal.
Once T is suppressed it might be possible to take a 7 day break every month without T shooting up. If E levels are good it should keep T down.
And it's a good idea to use the lowest dose possible.
Take all this with a grain of salt though because research on this is limited. It's really a ymmv thing. If what you're doing is working and you're happy with progress you can stick with it. If progress has stalled then it's probably time to try something different.
>>
>>11540794
A point in favor of bica is that because it isn't a progestin you can control your progesterone exposure without messing with your AA. But on the other hand cypro is a money saver and convenient because it's already a progestin. But you give up control over progestin dosing.



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